Mdm2: p53's lifesaver?

被引：35
|
作者：
Shmueli, Ayelet [1 ]
Oren, Moshe [1 ]
机构：
[1] Weizmann Inst Sci, Dept Mol Cell Biol, IL-76100 Rehovot, Israel
来源：
MOLECULAR CELL | 2007年 / 25卷 / 06期
关键词：
D O I：
10.1016/j.molcel.2007.03.006
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：794 / 796
页数：3
相关论文
共 50 条
  • [21] p53和mdm2基因
    沈行良
    翁启芳
    中国热带医学, 2007, (01) : 103 - 105
  • [22] mdm2/p53与肿瘤
    金永丽
    王靖华
    陈龙邦
    临床肿瘤学杂志, 2007, (06) : 469 - 471
  • [23] Regulation of p53 stability by Mdm2
    Michael H. G. Kubbutat
    Stephen N. Jones
    Karen H. Vousden
    Nature, 1997, 387 : 299 - 303
  • [24] Ribosomal protein S7 as a novel modulator of p53–MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function
    D Chen
    Z Zhang
    M Li
    W Wang
    Y Li
    E R Rayburn
    D L Hill
    H Wang
    R Zhang
    Oncogene, 2007, 26 : 5029 - 5037
  • [25] Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53
    Xirodimas, DP
    Stephen, CW
    Lane, DP
    EXPERIMENTAL CELL RESEARCH, 2001, 270 (01) : 66 - 77
  • [26] Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability
    Pant, Vinod
    Xiong, Shunbin
    Iwakuma, Tomoo
    Quintas-Cardama, Alfonso
    Lozano, Guillermina
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (29) : 11995 - 12000
  • [27] P53 α-helix mimetics antagonize p53/MDM2 interaction and activate p53
    Chen, LH
    Yin, H
    Farooqi, B
    Sebti, S
    Hamilton, AD
    Chen, JD
    MOLECULAR CANCER THERAPEUTICS, 2005, 4 (06) : 1019 - 1025
  • [28] MDM2 chaperones the p53 tumor suppressor
    Wawrzynow, Bartosz
    Zylicz, Alicja
    Wallace, Maura
    Hupp, Ted
    Zylicz, Maciej
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (45) : 32603 - 32612
  • [29] Mdm2 facilitates the association of p53 with the proteasome
    Kulikov, Roman
    Letienne, Justine
    Kaur, Manjit
    Grossman, Steven R.
    Arts, Janine
    Blattner, Christine
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (22) : 10038 - 10043
  • [30] Reactivation of p53 via MDM2 inhibition
    Kim, E. S.
    Shohet, J. M.
    CELL DEATH & DISEASE, 2015, 6 : e1936 - e1936
12345