Role of DNA measurements of head and neck tumors

被引:8
|
作者
Milroy, CM
Ferlito, A
Devaney, KO
Rinaldo, A
机构
[1] UNIV PADUA,DEPT OTOLARYNGOL,NUOVO POLICLIN,I-35128 PADUA,ITALY
[2] UNIV SHEFFIELD,DEPT FORENS PATHOL,SHEFFIELD,S YORKSHIRE,ENGLAND
[3] UNIV PADUA,DEPT OTOLARYNGOL,PADUA,ITALY
[4] UNIV MICHIGAN,DEPT PATHOL,ANN ARBOR,MI 48109
来源
关键词
D O I
10.1177/000348949710600919
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The measurement of DNA ploidy has been used as a tool to try to determine the prognosis of many neoplasms. DNA ploidy can be determined by flow cytometry or image analysis of a tumor. In squamous carcinomas of the head and neck, a poorer prognosis has been associated with nondiploid tumors. Similar results have been obtained from studies of salivary gland neoplasms. The role of DNA ploidy as a provider of independent information has yet to be determined. With rarer head and neck tumors, measurement of tumor ploidy has yet to be established as a valuable adjunct to routine light microscopic study.
引用
收藏
页码:801 / 804
页数:4
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