MLN0128, a Second-Generation mTOR Kinase Inhibitor, Disrupts Survival Signaling and Triggers Apoptosis in AML

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作者
Zeng, Zhihong [1 ]
Wang, Rui-Yu [1 ]
Shi, Yuexi [1 ]
Qiu, Yihua [1 ]
Mak, Duncan H. [2 ]
Coombes, Kevin [3 ]
Yoo, Suk Young [1 ]
Jessen, Katti [4 ]
Liu, Yi [5 ]
Rommel, Christian [6 ]
Kantarjian, Hagop M. [1 ]
Kornblau, Steven M. [1 ]
Fruman, David [7 ]
Andreeff, Michael [1 ]
Konopleva, Marina [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Sect Mol Hematol & Therapy, Houston, TX 77030 USA
[3] Ohio State Univ, Columbus, OH 43210 USA
[4] eFFECTOR Therapeut, San Diego, CA USA
[5] Wellspring Biosci, San Diego, CA USA
[6] 5Amgen Inc, Thousand Oaks, CA USA
[7] UC Irvine, Irvine, CA USA
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R5 [内科学];
学科分类号
1002 ; 100201 ;
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页数:3
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