Death receptors leave a caspase footprint that Smacs of XIAP

被引：43
作者：
Bratton, SB [1 ]
Cohen, GM
机构：
[1] Univ Texas, Coll Pharm, Div Pharmacol & Toxicol, Ctr Mol & Cellular Toxicol, Austin, TX 78712 USA
[2] Univ Leicester, MRC, Toxicol Unit, Leicester LE1 9HN, Leics, England
来源：
CELL DEATH AND DIFFERENTIATION | 2003年 / 10卷 / 01期
关键词：
D O I：
10.1038/sj.cdd.4401176
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：4 / 6
页数：3
相关论文
共 19 条
[1]   Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2 [J].
Adrain, C ;
Creagh, EM ;
Martin, SJ .
EMBO JOURNAL, 2001, 20 (23) :6627-6636
[2]   XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95-and Bax-induced apoptosis [J].
Bratton, SB ;
Lewis, J ;
Butterworth, M ;
Duckett, C ;
Cohen, GM .
CELL DEATH AND DIFFERENTIATION, 2002, 9 (09) :881-892
[3]   Apoptotic death sensor: an organelle's alter ego? [J].
Bratton, SB ;
Cohen, GM .
TRENDS IN PHARMACOLOGICAL SCIENCES, 2001, 22 (06) :306-315
[4]   Structural and biochemical basis of apoptotic activation by Smac/DIABLO [J].
Chai, JJ ;
Du, CY ;
Wu, JW ;
Kyin, S ;
Wang, XD ;
Shi, YG .
NATURE, 2000, 406 (6798) :855-862
[5]   TRAIL-induced apoptosis requires Bax-dependent mitochondria release of Smac/DIABLO [J].
Deng, YB ;
Lin, YH ;
Wu, XW .
GENES & DEVELOPMENT, 2002, 16 (01) :33-45
[6]   Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases [J].
Deveraux, QL ;
Leo, E ;
Stennicke, HR ;
Welsh, K ;
Salvesen, GS ;
Reed, JC .
EMBO JOURNAL, 1999, 18 (19) :5242-5251
[7]   Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition [J].
Du, CY ;
Fang, M ;
Li, YC ;
Li, L ;
Wang, XD .
CELL, 2000, 102 (01) :33-42
[8]   Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2 [J].
Haraguchi, M ;
Torii, S ;
Matsuzawa, S ;
Xie, ZH ;
Kitada, S ;
Krajewski, S ;
Yoshida, H ;
Mak, TW ;
Reed, JC .
JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (10) :1709-1720
[9]   Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL [J].
Huang, DCS ;
Hahne, M ;
Schroeter, M ;
Frei, K ;
Fontana, A ;
Villunger, A ;
Newton, K ;
Tschopp, J ;
Strasser, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (26) :14871-14876
[10]   Relief of extrinsic pathway inhibition by the bid-dependent mitochondrial release of smac in fas-mediated hepatocyte apoptosis [J].
Li, SC ;
Zhao, YG ;
He, X ;
Kim, TH ;
Kuharsky, DK ;
Rabinowich, H ;
Chen, J ;
Du, CY ;
Yin, XM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (30) :26912-26920
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