Retention in care and viral suppression in the PMTCT continuum at a large referral facility in western Kenya

被引:10
作者
Humphrey, John M. [1 ]
Songok, Julia [2 ]
Ofner, Susan [3 ]
Musick, Beverly [3 ]
Alera, Marsha [4 ]
Kipchumba, Bett [5 ]
McHenry, Megan S. [6 ]
Carlucci, James G. [6 ]
Park, Jun [7 ]
Mwangi, Winfred [5 ]
Yiannoutsos, Constantin [7 ]
Bakoyannis, Giorgos [7 ]
Wools-Kaloustian, Kara [1 ]
机构
[1] Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA
[2] Moi Univ, Dept Paediat, Coll Hlth Sci, Eldoret, Kenya
[3] Indiana Univ Sch Med, Dept Biostat, Indianapolis, IN 46202 USA
[4] Acad Model Providing Access Healthcare, Eldoret, Kenya
[5] Moi Teaching & Referral Hosp, Dept Reprod Hlth, Eldoret, Kenya
[6] Indiana Univ Sch Med, Dept Pediat, Indianapolis, IN 46202 USA
[7] Richard M Fairbanks Sch Publ Hlth, Dept Biostat, Indianapolis, IN USA
基金
美国国家卫生研究院;
关键词
HIV; Pregnant women; Mother-to-child transmission; Retention; Viremia; OPTION B PLUS; TO-CHILD TRANSMISSION; BREAST-FEEDING WOMEN; HIV-EXPOSED INFANTS; ANTIRETROVIRAL THERAPY; POSTPARTUM RETENTION; FOLLOW-UP; PREVENTION; PROGRAM; IMPACT;
D O I
10.1007/s10461-022-03666-w
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Medical records of pregnant and postpartum women living with HIV and their infants attending a large referral facility in Kenya from 2015 to 2019 were analyzed to identify characteristics associated with retention in care and viral suppression. Women were stratified based on the timing of HIV care enrollment: known HIV-positive (KHP; enrolled pre-pregnancy) and newly HIV-positive (NHP; enrolled during pregnancy). Associations with retention at 18 months postpartum and viral suppression (< 1000 copies/mL) were determined. Among 856 women (20% NHP), retention was 83% for KHPs and 53% for NHPs. Viral suppression was 88% for KHPs and 93% for NHPs, but 19% of women were missing viral load results. In a competing risk model, viral suppression increased by 18% for each additional year of age but was not associated with other factors. Overall, 1.9% of 698 infants with >= 1 HIV test result were HIV-positive. Tailored interventions are needed to promote retention and viral load testing, particularly for NHPs, in the PMTCT continuum.
引用
收藏
页码:3494 / 3505
页数:12
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