Electrospun starch nanofibers: Recent advances, challenges, and strategies for potential pharmaceutical applications

被引：178

作者：

Liu, Guodong ^{[1
,2
,3
]}

Gu, Zhengbiao ^{[1
,2
,3
]}

Hong, Yan ^{[1
,2
,3
]}

Cheng, Li ^{[1
,2
,3
]}

Li, Caiming ^{[1
,2
,3
]}

机构：

[1] Jiangnan Univ, State Key Lab Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

[2] Jiangnan Univ, Sch Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

[3] Jiangnan Univ, Collaborat Innovat Ctr Food Safety & Qual Control, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

来源：

JOURNAL OF CONTROLLED RELEASE | 2017年 / 252卷

基金：

中国国家自然科学基金;

关键词：

Starch; Electrospinning; Nanofibers; Drug delivery; Tissue engineering; Wound dressing; TISSUE-ENGINEERING SCAFFOLDS; DRUG-DELIVERY SYSTEMS; HIGH-AMYLOSE STARCH; COMPOSITE NANOFIBERS; POLY(VINYL ALCOHOL); CROSS-LINKING; RHEOLOGICAL PROPERTIES; SURFACE MODIFICATION; DEBRANCHED STARCHES; FORMING NANOFIBRES;

D O I：

10.1016/j.jconrel.2017.03.016

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electrospun starch nanofibers have high porosity, extremely high specific surface area, and biocompatible, biodegradable, and bioabsorbable properties. As a result, starch nanofibers have great potential in pharmaceutical applications, including drug delivery, wound dressing, and tissue engineering. Here, we summarize and review the recent developments in the synthesis of electrospun starch fibers from common starch, modified starch, and hybrids with other polymers. Moreover, the challenges and strategies for the fabrication and application of starch fibers in pharmaceutical applications are presented. (C) 2017 Elsevier B. V. All rights reserved.

引用

页码：95 / 107

页数：13

共 105 条

[61] Cross-Linking of Gelatin and Chitosan Complex Nanofibers for Tissue-Engineering Scaffolds [J].

Qian, Yong-Fang ;

Zhang, Kui-Hua ;

Chen, Feng ;

Ke, Qin-Fei ;

Mo, Xiu-Mei .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2011, 22 (08) :1099-1113

[62] Nanometre diameter fibres of polymer, produced by electrospinning [J].

Reneker, DH ;

Chun, I .

NANOTECHNOLOGY, 1996, 7 (03) :216-223

[63] Application of Cellulosic Nanofibers in Food Science Using Electrospinning and Its Potential Risk [J].

Rezaei, Atefe ;

Nasirpour, Ali ;

Fathi, Milad .

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2015, 14 (03) :269-284

[64] Designing electrospun nanofiber mats to promote wound healing - a review [J].

Rieger, Katrina A. ;

Birch, Nathan P. ;

Schiffman, Jessica D. .

JOURNAL OF MATERIALS CHEMISTRY B, 2013, 1 (36) :4531-4541

[65] New wound dressing polymeric nanofiber containing green tea extract prepared by electrospinning method [J].

Sadri, Minoo ;

Arab-Sorkhi, Saedeh ;

Vatani, Hossein ;

Bagheri-Pebdeni, Azam .

FIBERS AND POLYMERS, 2015, 16 (08) :1742-1750

[66] Surface modification of electrospun fibres for biomedical applications: A focus on radical polymerization methods [J].

Sanchez, Lina Duque ;

Brack, Narelle ;

Postma, Almar ;

Pigram, Paul J. ;

Meagher, Laurence .

BIOMATERIALS, 2016, 106 :24-45

[67] Printed Drug-Delivery Systems for Improved Patient Treatment [J].

Sandler, Niklas ;

Preis, Maren .

TRENDS IN PHARMACOLOGICAL SCIENCES, 2016, 37 (12) :1070-1080

[68] Cross-linking methods of electrospun fibrinogen scaffolds for tissue engineering applications [J].

Sell, Scott A. ;

Francis, Michael P. ;

Garg, Koyal ;

McClure, Michael J. ;

Simpson, David G. ;

Bowlin, Gary L. .

BIOMEDICAL MATERIALS, 2008, 3 (04)

[69] Printing Technologies for Medical Applications [J].

Shafiee, Ashkan ;

Atala, Anthony .

TRENDS IN MOLECULAR MEDICINE, 2016, 22 (03) :254-265

[70] Near-infrared light-responsive nanomaterials in cancer therapeutics [J].

Shanmugam, Vijayakumar ;

Selvakumar, S. ;

Yeh, Chen-Sheng .

CHEMICAL SOCIETY REVIEWS, 2014, 43 (17) :6254-6287

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