Surface-Enhanced Raman Spectroscopy Study of 4-ATP on Gold Nanoparticles for Basal Cell Carcinoma Fingerprint Detection

被引：22

作者：

Luu Manh Quynh ^{[1
]}

Nguyen Hoang Nam ^{[1
,2
]}

Kong, K. ^{[3
]}

Nguyen Thi Nhung ^{[1
]}

Notingher, I. ^{[3
]}

Henini, M. ^{[3
]}

Nguyen Hoang Luong ^{[2
]}

机构：

[1] Vietnam Natl Univ, Hanoi Univ Sci, Fac Phys, 334 Nguyen Trai, Hanoi, Vietnam

[2] Vietnam Natl Univ, Hanoi Univ Sci, Nano & Energy Ctr, Hanoi, Vietnam

[3] Univ Nottingham, Sch Phys & Astron, Univ Pk, Nottingham NG7 2RD, England

来源：

JOURNAL OF ELECTRONIC MATERIALS | 2016年 / 45卷 / 05期

基金：

美国国家卫生研究院;

关键词：

Skin cancer; basal cell carcinoma; surface-enhanced Raman scattering; gold nanoparticles; SCATTERING; SILVER; ASSEMBLIES; SURGERY; TISSUE; SERS;

D O I：

10.1007/s11664-016-4421-9

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The surface-enhanced Raman signals of 4-aminothiophenol (4-ATP) attached to the surface of colloidal gold nanoparticles with size distribution of 2 to 5 nm were used as a labeling agent to detect basal cell carcinoma (BCC) of the skin. The enhanced Raman band at 1075 cm(-1) corresponding to the C-S stretching vibration in 4-ATP was observed during attachment to the surface of the gold nanoparticles. The frequency and intensity of this band did not change when the colloids were conjugated with BerEP4 antibody, which specifically binds to BCC. We show the feasibility of imaging BCC by surface-enhanced Raman spectroscopy, scanning the 1075 cm(-1) band to detect the distribution of 4-ATP-coated gold nanoparticles attached to skin tissue ex vivo.

引用

页码：2563 / 2568

页数：6

共 27 条

[1] Surface-enhanced Raman scattering detection of the breast cancer susceptibility gene BRCA1 using a silver-coated microarray platform
Allain, LR
Vo-Dinh, T
[J]. ANALYTICA CHIMICA ACTA, 2002, 469 (01) : 149 - 154
[2] Facial basal cell carcinoma
Baxter, Julia M.
Patel, Anand N.
Varma, Sandeep
[J]. BMJ-BRITISH MEDICAL JOURNAL, 2012, 345
[3] RAMAN-SPECTRA OF PYRIDINE ADSORBED AT A SILVER ELECTRODE
FLEISCHMANN, M
HENDRA, PJ
MCQUILLAN, AJ
[J]. CHEMICAL PHYSICS LETTERS, 1974, 26 (02) : 163 - 166
[4] Distinctive molecular abnormalities in benign and malignant skin lesions: Studies by Raman spectroscopy
Gniadecka, M
Wulf, HC
Nielsen, OF
Christensen, DH
Hercogova, J
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1997, 66 (04) : 418 - 423
[5] SURFACE-ENHANCED RAMAN-SPECTROSCOPY OF TRIPEPTIDES ADSORBED ON COLLOIDAL SILVER
HERNE, TM
AHERN, AM
GARRELL, RL
[J]. ANALYTICA CHIMICA ACTA, 1991, 246 (01) : 75 - 84
[6] Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods
Huang, XH
El-Sayed, IH
Qian, W
El-Sayed, MA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (06) : 2115 - 2120
[7] In situ electrochemical SERS studies on electrodeposition of aniline on 4-ATP/Au surface
Jiao, Lian-sheng
Wang, Zhijuan
Niu, Li
Shen, Jing
You, Tian-yan
Dong, Shao-jun
Ivaska, Ari
[J]. JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 2006, 10 (11) : 886 - 893
[8] Simple azo derivatization on 4-aminothiophenol/Au monolayer
Jiao, LS
Niu, L
Shen, J
You, TY
Dong, SJ
Ivaska, A
[J]. ELECTROCHEMISTRY COMMUNICATIONS, 2005, 7 (02) : 219 - 222
[9] Surface enhanced Raman scattering from layered assemblies of close-packed gold nanopardicles
Jung, Hye Young
Park, Yong-Kyun
Park, Sunyho
Kim, Seong Kyu
[J]. ANALYTICA CHIMICA ACTA, 2007, 602 (02) : 236 - 243
[10] Physical Origins of Chemical Enhancement of Surface-Enhanced Raman Spectroscopy on a Gold Nanoparticle-Coated Polymer
Kim, Nam-Jung
[J]. JOURNAL OF PHYSICAL CHEMISTRY C, 2010, 114 (33) : 13979 - 13984

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