Executive function, episodic memory, and Medicare expenditures

被引:30
作者
Bender, Alex C. [1 ]
Austin, Andrea M. [2 ]
Grodstein, Francine [3 ]
Bynum, Julie P. W. [2 ]
机构
[1] Geisel Sch Med Dartmouth, Hanover, NH USA
[2] Geisel Sch Med Dartmouth, Dartmouth Inst Hlth Policy & Clin Practice, Hanover, NH 03755 USA
[3] Harvard Med Sch, Brigham & Womens Hosp, Channing Div Network Med, Boston, MA USA
基金
美国国家卫生研究院;
关键词
Medicare; Dementia; Cognition; Aging; Executive function; Episodic memory; Health care spending; MILD COGNITIVE IMPAIRMENT; MINI-MENTAL-STATE; ALZHEIMERS-DISEASE; INSTRUMENTAL ACTIVITIES; TELEPHONE VERSION; DEMENTIA; COSTS; AGE; VALIDATION; CONSORTIUM;
D O I
10.1016/j.jalz.2016.12.013
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: We examined the relationship between health care expenditures and cognition, focusing on differences across cognitive systems defined by global cognition, executive function, or episodic memory. Methods: We used linear regression models to compare annual health expenditures by cognitive status in 8125 Nurses' Health Study participants who completed a cognitive battery and were enrolled in Medicare parts A and B. Results: Adjusting for demographics and comorbidity, executive impairment was associated with higher total annual expenditures of $ 1488 per person (P < .01) compared with those without impairment. No association for episodic memory impairment was found. Expenditures exhibited a linear relationship with executive function, but not episodic memory ($ 584 higher for every 1 standard deviation decrement in executive function; P < .01). Discussion: Impairment in executive function is specifically and linearly associated with higher health care expenditures. Focusing on management strategies that address early losses in executive function may be effective in reducing costly services. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:792 / 800
页数:9
相关论文
共 51 条
[21]   Postmenopausal hormone therapy and cognitive function in healthy older women [J].
Grodstein, F ;
Chen, J ;
Pollen, DA ;
Albert, MS ;
Wilson, RS ;
Folstein, MF ;
Evans, DA .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2000, 48 (07) :746-752
[22]   Differences in resource use and costs of dementia care between European countries: Baseline data from the ictus study [J].
Gustavsson, A. ;
Jonsson, L. ;
Rapp, T. ;
Reynish, E. ;
Ousset, P. J. ;
Andrieu, S. ;
Cantet, C. ;
Winblad, B. ;
Vellas, B. ;
Wimo, A. .
JOURNAL OF NUTRITION HEALTH & AGING, 2010, 14 (08) :648-654
[23]   Natural Progression Model of Cognition and Physical Functioning among People with Mild Cognitive Impairment and Alzheimer's Disease [J].
Handels, Ron L. H. ;
Xu, Weili ;
Rizzuto, Debora ;
Caracciolo, Barbara ;
Wang, Rui ;
Winblad, Bengt ;
Verhey, Frans R. J. ;
Severens, Johan L. ;
Fratiglioni, Laura ;
Joore, Manuela A. ;
Wimo, Anders .
JOURNAL OF ALZHEIMERS DISEASE, 2013, 37 (02) :357-365
[24]   Cognitive impairment in epilepsy: the role of network abnormalities [J].
Holmes, Gregory L. .
EPILEPTIC DISORDERS, 2015, 17 (02) :101-116
[25]  
Hurd MD, 2013, NEW ENGL J MED, V369, P489, DOI [10.1056/NEJMsa1204629, 10.1056/NEJMc1305541]
[26]   The Pathobiology of Vascular Dementia [J].
Iadecola, Costantino .
NEURON, 2013, 80 (04) :844-866
[27]   An Empirical Comparison of the Therapeutic Benefits of Physical Exercise and Cognitive Training on the Executive Functions of Older Adults: A Meta-Analysis of Controlled Trials [J].
Karr, Justin E. ;
Areshenkoff, Corson N. ;
Rast, Philippe ;
Garcia-Barrera, Mauricio A. .
NEUROPSYCHOLOGY, 2014, 28 (06) :829-845
[28]   RELIABILITY OF THE BLESSED TELEPHONE INFORMATION-MEMORY-CONCENTRATION TEST [J].
KAWAS, C ;
KARAGIOZIS, H ;
RESAU, L ;
CORRADA, M ;
BROOKMEYER, R .
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY, 1995, 8 (04) :238-242
[29]   Costs explained by function rather than diagnosis-results from the SNAC Nordanstig elderly cohort in Sweden [J].
Lindholm, C. ;
Gustavsson, A. ;
Jonsson, L. ;
Wimo, A. .
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2013, 28 (05) :454-462
[30]   Exercise Training and Recreational Activities to Promote Executive Functions in Chronic Stroke: A Proof-of-concept Study [J].
Liu-Ambrose, Teresa ;
Eng, Janice J. .
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2015, 24 (01) :130-137