Toll-Like Receptors in Dermatology, Venereology, and Leprosy

被引:3
作者
Gandhi, Sneha [1 ]
Ravindra, K. [2 ]
机构
[1] GIMS, Dept Dermatol Venereol & Leprosy, Gulbarga, Karnataka, India
[2] JJMMC, Dept Dermatol Venereol & Leprosy, Davangere, Karnataka, India
关键词
Acne; atopic dermatitis; psoriasis; toll-like receptors; ACTIVATION; EXPRESSION; KERATINOCYTES; PATHOGENESIS; IMPAIRMENT; MODULATION; TLR2;
D O I
10.4103/ijd.IJD_486_17
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Toll-like receptors (TLRs) represent a family of Type I transmembrane proteins characterized by an extracellular leucine-rich repeat domain and a cytoplasmic domain. TLRs represent a conserved group of receptors which help the immune system to function properly. Different TLRs are associated with an array of skin diseases. TLR agonists and antagonists have great potential for the treatment of allergic and inflammatory diseases.
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