Outcomes following surgical decompression for dysthyroid orbitopathy (Graves' disease)

被引:36
|
作者
Leong, Samuel C. [2 ]
White, Paul S. [1 ]
机构
[1] Univ Dundee, Ninewells Hosp & Med Sch, Dept Otolaryngol Head & Neck Surg, Dundee DD1 9SY, Scotland
[2] Alder Hey Childrens NHS Fdn Trust, Dept Paediat Otolaryngol Head & Neck Surg, Liverpool, Merseyside, England
关键词
decompression; dysthyroid orbitopathy; Graves' disease; ophthalmopathy; surgery; ENDOSCOPIC ORBITAL DECOMPRESSION; OF-LIFE QUESTIONNAIRE; THYROID EPIDEMIOLOGY; ENDONASAL APPROACH; OPHTHALMOPATHY; TRANSNASAL; AUDIT;
D O I
10.1097/MOO.0b013e328335017c
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Purpose of review Graves' disease is a multiorgan autoimmune disease of complex pathophysiology that primarily affects the thyroid gland and orbit. The ophthalmic manifestations of Graves' disease may vary from mild proptosis which causes minimal cosmetic embarrassment to subluxation of the globe, exposure keratitis, corneal abrasion and even blindness. This article focuses on outcomes comes following orbital decompression. Recent findings Surgical techniques have evolved with improved understanding of sinonasal anatomy and being technology-cl riven with the use of the fiberoptic endoscope and image guidance. The most common surgical outcome reported in the literature is reduction in proptosis, followed by visual acuity and intraocular pressure. Quality-of-life assessments are not routinely measured. Summary There are a myriad of surgical techniques currently in practice which underscores the fact that no single technique is clearly superior to another. Endoscopic decompression results in a mean reduction of 3.50 mm and is associated with a low complication rate. Nevertheless, the literature suggests that the best techniques are likely to be multiwall approaches such as combined medial and lateral wall decompression. Management of dysthyroid ophthalmopathy is clearly multidisciplinary. Future studies should consider a minimum data set for reporting outcome measures which should include a quality of life tool.
引用
收藏
页码:37 / 43
页数:7
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