Modified model of the structure of the potato virus X coat protein

被引：2

作者：

Dobrov, E. N. ^{[1
]}

Nemykh, M. A.

Lukashina, E. V.

Baratova, L. A.

Drachev, V. A.

Efimov, A. V.

机构：

[1] Moscow MV Lomonosov State Univ, Belozersky Inst Phys Chem Biol, Moscow 119992, Russia

[2] Moscow MV Lomonosov State Univ, Fac Bioengn & Bioinformat, Moscow 119992, Russia

[3] Russian Acad Sci, Inst Prot Res, Moscow 142290, Russia

来源：

MOLECULAR BIOLOGY | 2007年 / 41卷 / 04期

基金：

俄罗斯基础研究基金会;

关键词：

potato virus X; model of coat protein structure;

D O I：

10.1134/S0026893307040176

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A modified model was proposed for the tertiary structure of the coat protein (CP) molecules in potato virus X (PVX) virions, similar to the original model of 2001 describing the structure of CP of potato virus A, a member of another group of filamentous viruses. According to the new model, CP comprises two main structural domains, namely, a bundle of alpha-helices, located near the long axis of the virion, and the socalled RNP fold (or abCd fold), located in the vicinity of its surface. The model made it possible to suggest a possible mechanism of the PVX virion structural rearrangement (remodeling) resulting from translational activation of virions by the TGB1 movement protein according to Atabekov and colleagues.

引用

页码：638 / 641

页数：4

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