Monte Carlo-assisted voxel source kernel method (MAVSK) for internal beta dosimetry

被引：20
作者：
Liu, A
Williams, LE
Wong, JYC
Raubitschek, AA
机构：
[1] City Hope Natl Med Ctr, Div Radiol, Duarte, CA 91010 USA
[2] Univ Calif Los Angeles, Med Ctr, Dept Radiol Sci, Los Angeles, CA 90024 USA
[3] City Hope Natl Med Ctr, Div Radiat Oncol, Duarte, CA 91010 USA
[4] City Hope Natl Med Ctr, Dept Radioimmunotherapy, Duarte, CA 91010 USA
来源：
NUCLEAR MEDICINE AND BIOLOGY | 1998年 / 25卷 / 04期
关键词：
absorbed beta dose; Y-90; radioimmunotherapy;
D O I：
10.1016/S0969-8051(98)00002-X
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A method is described for the determination of patient specific organ beta doses given a known cumulated internal radioactivity distribution. A voxel source kernel for Y-90 analogous to the point source function was simulated. Dose to each organ of interest could then be estimated by convolving the voxel source kernel with the patient's 3-D volume with known radioactivity assigned to each voxel. The dose calculation on eight organs took less than 1 min per patient using a Sun Sparc10 workstation. (C) 1998 Elsevier Science Inc.
引用
收藏
页码：423 / 433
页数：11
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