Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia

被引：15

作者：

Alanazi, Abdullah D. ^{[1
]}

Alouffi, Abdulazi S. ^{[2
]}

Alyousif, Mohamed S. ^{[3
]}

Rahi, Abdulsadah A. ^{[4
]}

Ali, Magda A. ^{[4
]}

Abdullah, Hend H. A. M. ^{[5
]}

Brayner, Fabio A. ^{[6
]}

Mendoza-Roldan, Jairo Alfonso ^{[7
]}

Bezerra-Santos, Marcos Antonio ^{[7
]}

Otranto, Domenico ^{[7
,8
]}

机构：

[1] Shaqra Univ, Dept Biol Sci, Fac Sci & Humanities, POB 1040, Ad Dawadimi 11911, Saudi Arabia

[2] King Abdulaziz City Sci & Technol, Riyadh, Saudi Arabia

[3] King Saud Univ, Coll Sci, Dept Zool, Riyadh, Saudi Arabia

[4] Univ Wasit, Coll Sci, Dept Biol, Kut 00964, Wasit, Iraq

[5] Natl Res Ctr, Dept Parasitol & Anim Dis, Vet Res Div, 33 Bohouth St, Giza 12622, Egypt

[6] Univ Fed Pernambuco, Lab Imunopatol Keizo Asami, BR-50670901 Recife, PE, Brazil

[7] Univ Bari, Dipartimento Med Vet, Bari, Italy

[8] Bu Ali Sina Univ, Fac Vet Sci, Hamadan, Hamadan, Iran

来源：

PARASITOLOGY RESEARCH | 2021年 / 120卷 / 12期

关键词：

Leishmania tropica; Leishmania major; Dogs; Patients; kDNA; nPCR; Saudi Arabia; CUTANEOUS LEISHMANIASIS; INFECTING MAN; WILD ANIMALS; VISCERAL LEISHMANIASIS; CLINICAL-FEATURES; PROVINCE; TROPICA; IDENTIFICATION; EPIDEMIOLOGY; DIAGNOSIS;

D O I：

10.1007/s00436-021-07166-z

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Leishmania major and Leishmania tropica cause cutaneous leishmaniasis in humans and dogs in several parts of the world, with a large number of cases recorded in the Middle East. However, when they occur in sympatry, the role of each species of Leishmania in the epidemiology of cutaneous leishmaniasis (CL) is not clear. To assess the frequency and to identify the species of Leishmania that infect humans and stray dogs in Riyadh and Al-Qaseem (Saudi Arabia), 311 stray dogs and 27 human patients who were suspected for Leishmania infection were examined for CL by a nested polymerase chain reaction (nPCR). Seven (25.9%) out of 27 human patients scored positive for Leishmania spp. (i.e., L. major in five patients from Riyadh and L. tropica in two patients from Al-Qaseem). Out of 311 dogs, five (1.6%) were infected by L. tropica. Data herein presented demonstrate the occurrence of L. tropica in dogs and humans in Saudi Arabia, as well as the occurrence of L. major in humans.

引用

页码：4241 / 4246

页数：6

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