Dynamic host-guest interaction enables autonomous single molecule blinking and super-resolution imaging

被引：17
作者：
Sasmal, Ranjan [1 ]
Das Saha, Nilanjana [1 ,2 ]
Schueder, Florian [3 ,4 ,5 ]
Joshi, Divyesh [6 ]
Sheeba, Vasu [7 ]
Jungmann, Ralf [3 ,4 ,5 ]
Agasti, Sarit S. [1 ,2 ]
机构：
[1] JNCASR, New Chem Unit, Bangalore 560064, Karnataka, India
[2] JNCASR, Chem & Phys Mat Unit, Bangalore 560064, Karnataka, India
[3] Max Planck Inst Biochem, D-82152 Martinsried, Germany
[4] Ludwig Maximillian Univ, Dept Phys, D-80539 Munich, Germany
[5] Ludwig Maximillian Univ, Ctr Nanosci, D-80539 Munich, Germany
[6] JNCASR, Mol Biol & Genet Unit, Bangalore 560064, Karnataka, India
[7] JNCASR, Neurosci Unit, Bangalore 560064, Karnataka, India
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 96期
基金：
欧洲研究理事会; 英国惠康基金;
关键词：
SUPRAMOLECULAR CONTROL; BINDING; MICROSCOPY; CHEMISTRY; RELEASE;
D O I：
10.1039/c9cc07153a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthetic host-guest complexes are inherently dynamic as they employ weak and reversible noncovalent interactions for their recognition processes. We strategically exploited dynamic supramolecular recognition between fluorescently labeled guest molecules to complementary cucurbit[7]uril hosts to obtain stochastic switching between fluorescence ON- and OFF-states, enabling PAINT-based nanoscopic imaging in cells and tissues.
引用
收藏
页码：14430 / 14433
页数：4
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