COVID-19 and HIV infection co-pandemics and their impact: a review of the literature

被引:66
作者
Gatechompol, Sivaporn [1 ,2 ]
Avihingsanon, Anchalee [1 ,2 ]
Putcharoen, Opass [3 ]
Ruxrungtham, Kiat [4 ]
Kuritzkes, Daniel R. [5 ]
机构
[1] Thai Red Cross AIDS Res Ctr, HIV NAT, Bangkok, Thailand
[2] Chulalongkorn Univ, Fac Med, TB Res Unit, Bangkok, Thailand
[3] Chulalongkorn Univ, Fac Med, Dept Med, Div Infect Dis, Bangkok, Thailand
[4] Chulalongkorn Univ, Fac Med, Chula Vaccine Res Ctr, ChulaVRC, Bangkok, Thailand
[5] Harvard Med Sch, Brigham & Womens Hosp, Div Infect Dis, Boston, MA 02115 USA
基金
英国科研创新办公室;
关键词
COVID-19; HIV; Co-infection; Pathophysiology; Clinical; Outcome; CORONAVIRUS; PATHOGENESIS; PEOPLE; SARS;
D O I
10.1186/s12981-021-00335-1
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Coronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus on 4 topics: (1) the pathophysiology and host immune response of people infected with both SARS-CoV-2 and HIV, (2) present the clinical manifestations and treatment outcomes of persons with co-infection, (3) assess the impact of antiretroviral HIV drugs among PLWH infected with COVID-19 and (4) evaluate the impact of the COVID-19 pandemic on HIV services.
引用
收藏
页数:9
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