Higher Ultrafiltration Rate Is Associated with Longer Dialysis Recovery Time in Patients Undergoing Conventional Hemodialysis

被引:36
作者
Hussein, Wael F. [1 ,2 ]
Arrannreddy, Rohini [1 ,2 ]
Sun, Sumi J. [2 ]
Reiterman, Marc [2 ]
Schiller, Brigitte [1 ,2 ]
机构
[1] Stanford Univ, Div Nephrol, Dept Med, Palo Alto, CA 94304 USA
[2] Satellite Healthcare, San Jose, CA USA
关键词
Hemodialysis; Ultrafiltration; Minutes to recovery; Recovery time; Quality of life; Fatigue; QUALITY-OF-LIFE; STAGE RENAL-DISEASE; INTRADIALYTIC HYPOTENSION; MAINTENANCE HEMODIALYSIS; CARDIOVASCULAR-DISEASE; KIDNEY-DISEASE; SERUM-ALBUMIN; MORTALITY; HEALTH; OUTCOMES;
D O I
10.1159/000476076
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Background: Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. Methods: This is a cross-sectional, observational study was conducted. Patients on thrice weekly hemodialysis (HD) with self-reported DRT between August and December 2014 were included. We examined the association of 30-day average UFR with recovery time. Results: The total number of patients included in this study was 2,689. DRT in categories of immediate recovery, > 0-<= 2, > 2-<= 6, > 6-<= 12, and >12 h, were reported in 27, 28,17, 9, and 20% of the patients respectively. In multivariable analysis, longer DRT was associated with female gender, non-black race, higher body weight, lower serum albumin, chronic heart failure, cerebrovascular disease, missed dialysis sessions, higher pre-dialysis systolic blood pressure, and larger OF volume. Compared to UFR of <10, UFR <equal to or greater than> 13 mL/kg/h was associated with longer DRT, OR of 1.16 (95% CI 0.99-1.36), and 1.28 (95% CI 1.06-1.54) in the unadjusted and the adjusted analyses respectively. Intradialytic hypotension was also associated with longer DRT in the unadjusted (per 10% higher frequency, OR 1.04 [95% CI 1.01-1.07]) and adjusted analyses (OR 1.03 [95% CI 1.00-1.07]). Conclusion: Long recovery time is common after HD. Rapid fluid removal is associated with longer DRT. (C) 2017 S. Karger AG, Basel
引用
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页码:3 / 10
页数:8
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