Quantitative constraints on the scope of negative selection: robustness and weaknesses

被引：5

作者：

Bandeira, A

Faro, J

机构：

[1] Inst Pasteur, Unite Dev Lymphocytes, F-75724 Paris 15, France

[2] Gulbenkian Inst Sci, P-2781901 Oeiras, Portugal

来源：

TRENDS IN IMMUNOLOGY | 2003年 / 24卷 / 04期

关键词：

D O I：

10.1016/S1471-4906(03)00055-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：172 / 173

页数：2

共 10 条

[1] HOW DIVERSE SHOULD THE IMMUNE-SYSTEM BE [J].

DEBOER, RJ ;

PERELSON, AS .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1993, 252 (1335) :171-175

[2] A quantitative theory of affinity-driven T cell repertoire selection [J].

Detours, V ;

Mehr, R ;

Perelson, AS .

JOURNAL OF THEORETICAL BIOLOGY, 1999, 200 (04) :389-403

[3] The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation [J].

Germain, RN ;

Stefanova, I .

ANNUAL REVIEW OF IMMUNOLOGY, 1999, 17 :467-522

[4] Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain:: A role in the generation of positively selecting peptide ligands [J].

Honey, K ;

Nakagawa, T ;

Peters, C ;

Rudensky, A .

JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 195 (10) :1349-1358

[5]

JAMESON SC, 1995, ANNU REV IMMUNOL, V13, P93, DOI 10.1146/annurev.iy.13.040195.000521

[6] A very high level of crossreactivity is an essential feature of the T-cell receptor [J].

Mason, D .

IMMUNOLOGY TODAY, 1998, 19 (09) :395-404

[7]

MULLER, 2003, TRENDS IMMUNOL, V24, P132

[8] Antigen receptor 'capacity' and the sensitivity of self-tolerance [J].

Nemazee, D .

IMMUNOLOGY TODAY, 1996, 17 (01) :25-29

[9] A reliable and safe T cell repertoire based on low-affinity T cell receptors [J].

Van Den Berg, HA ;

Rand, DA ;

Burroughs, NJ .

JOURNAL OF THEORETICAL BIOLOGY, 2001, 209 (04) :465-486

[10] Quantitative impact of thymic clonal deletion on the T cell repertoire [J].

vanMeerwijk, JPM ;

Marguerat, S ;

Lees, RK ;

Germain, RN ;

Fowlkes, BJ ;

MacDonald, HR .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (03) :377-383

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