Covalently supported porphyrins as ligands for the preparation of heme a3/CuB binuclear active site analogues of heme-copper terminal oxidases and metallation under mild conditions

被引：30

作者：

Baeg, JO ^{[1
]}

Holm, RH ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 05期

关键词：

D O I：

10.1039/a707785h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New covalently supported binucleating porphyrins have been prepared as potential structural and/or functional ligands for the iron-copper theme a(3)/Cu-B) active sites of heme-copper oxidases, and the introduction of iron and copper into one porphyrin under mild reaction conditions has been developed.

引用

页码：571 / 572

页数：2

共 25 条

[1] OXYGEN ACTIVATION AND THE CONSERVATION OF ENERGY IN CELL RESPIRATION [J].

BABCOCK, GT ;

WIKSTROM, M .

NATURE, 1992, 356 (6367) :301-309

[2] CONGRUENT MULTIPLE MICHAEL ADDITION FOR THE SYNTHESIS OF BIOMIMETIC HEME ANALOGS [J].

COLLMAN, JP ;

ZHANG, XM ;

HERRMANN, PC ;

UFFELMAN, ES ;

BOITREL, B ;

STRAUMANIS, A ;

BRAUMAN, JI .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (06) :2681-2682

[3] A functional model related to cytochrome c oxidase and its electrocatalytic four-electron reduction of O-2 [J].

Collman, JP ;

Fu, L ;

Herrmann, PC ;

Zhang, XM .

SCIENCE, 1997, 275 (5302) :949-951

[4] Aza-crown-capped porphyrin models of myoglobin: Studies of the steric interactions of gas binding [J].

Collman, JP ;

Herrmann, PC ;

Fu, L ;

Eberspacher, TA ;

Eubanks, M ;

Boitrel, B ;

Hayoz, P ;

Zhang, XM ;

Brauman, JI ;

Day, VW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (15) :3481-3489

[5] A SYNTHETIC ANALOG FOR THE OXYGEN-BINDING SITE IN CYTOCHROME-C-OXIDASE [J].

COLLMAN, JP ;

HERRMANN, PC ;

BOITREL, B ;

ZHANG, XM ;

EBERSPACHER, TA ;

FU, L ;

WANG, JL ;

ROUSSEAU, DL ;

WILLIAMS, ER .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (21) :9783-9784

[6] Functional analogs of heme protein active sites [J].

Collman, JP .

INORGANIC CHEMISTRY, 1997, 36 (23) :5145-5155

[7] PICKET-FENCE PORPHYRINS - SYNTHETIC MODELS FOR OXYGEN BINDING HEMOPROTEINS [J].

COLLMAN, JP ;

GAGNE, RR ;

REED, CA ;

HALBERT, TR ;

LANG, G ;

ROBINSON, WT .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (06) :1427-1439

[8] FAST REACTIONS OF CYTOCHROME-OXIDASE [J].

EINARSDOTTIR, O .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1995, 1229 (02) :129-147

[9] Heme/copper terminal oxidases [J].

FergusonMiller, S ;

Babcock, GT .

CHEMICAL REVIEWS, 1996, 96 (07) :2889-2907

[10] Vibrational analysis of a molecular heme-copper assembly with a nearly linear Fe-III-CN-Cu-II bridge: Insight into cyanide binding to fully oxidized cytochrome c oxidase [J].

Gardner, MT ;

Deinum, G ;

Kim, Y ;

Babcock, GT ;

Scott, MJ ;

Holm, RH .

INORGANIC CHEMISTRY, 1996, 35 (23) :6878-6884

← 1 2 3 →