Pain and Depression: A Neurobiological Perspective of Their Relationship

被引：78

作者：

Han, Changsu ^{[1
]}

Pae, Chi-Un ^{[2
,3
]}

机构：

[1] Korea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea

[2] Catholic Univ Korea, Coll Med, Bucheon St Marys Hosp, Dept Psychiat, Puchon 420717, South Korea

[3] Duke Univ, Med Ctr, Dept Psychiat & Behav Sci, Durham, NC USA

来源：

PSYCHIATRY INVESTIGATION | 2015年 / 12卷 / 01期

关键词：

Depression; Pain; Relationship; Pathophysiology; Symptomatology; Treatment; LOW-BACK-PAIN; DOUBLE-BLIND; PSYCHIATRIC-DISORDERS; SUICIDAL IDEATION; MENTAL-DISORDERS; OLDER-ADULTS; SUBSTANCE-P; FIBROMYALGIA; ASSOCIATION; SYMPTOMS;

D O I：

10.4306/pi.2015.12.1.1

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Remarkable progresses have been achieved regarding the understanding of the neurobiological bases of pain and depression. The principal role of neurotiansmitters, neuromodulators, and neurohormones has been proposed in the development of pain and depression. With the progression of molecular biology, an intricate interaction among biological factors accountable to the development and management of pain and depression has been also shown in a numerous predinical and clinical researches. This mini-review will briefly describe the current issues and future research direction for better understanding of the relationship between pain and depression.

引用

页码：1 / 8

页数：8

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