An ultrasensitive and selective method for the determination of Ceftriaxone using cysteine capped cadmium sulfide fluorescence quenched quantum dots as fluorescence probes

被引：20
作者：
Samadi, Naser [1 ]
Narimani, Saeedeh [1 ]
机构：
[1] Urmia Univ, Dept Chem, Fac Sci, Orumiyeh, Iran
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2016年 / 163卷
关键词：
CdS quantum dots; L-cysteine; Probe; Ceftriaxone; CHROMATOGRAPHY-MASS SPECTROMETRY; PHARMACEUTICAL FORMULATIONS; DOSAGE FORMS; METAL-IONS; RP-HPLC; COPPER(II); NANOPARTICLES; NANOCRYSTALS; SODIUM; WATER;
D O I：
10.1016/j.saa.2016.03.014
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
In this paper, L-cysteine (Cys) coated CdS quantum dots (QDs) have been prepared, which have excellent water solubility and are highly stable in aqueous solution. These QDs is proposed as sensitizers for the determination of Ceftriaxone. The quantum dot nanoparticles were structurally and optically characterized by Ultra Violet-Visible absorption Spectroscopy (UV-vis absorption spectroscopy), Fourier transform infrared spectroscopy (FT-IR spectra) and photoluminescence (PL) emission spectroscopy. High resolution transmission electron microscopy (HRTEM) confirms that the Cys-CdS QDs have a spherical structure with good crystallinity. Therefore, a new simple and selective PL analysis system was developed for the determination of Ceftriaxone (CFX). Under the optimum conditions, The response of L-Cys capped CdS QDs as the probe was linearly proportional to the concentration of Ceftriaxone ions in the range of 1.6 x 10(-9)-1.1 x 10(-3) M with a correlation coefficient (R-2) of 0.9902. The limit of detection of this system was found to be 1.3 nM. This method is simple, sensitive and low cost. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：8 / 12
页数：5
相关论文
共 47 条
[1]   Simultaneous determination of metronidazole and miconazole in pharmaceutical dosage forms by RP-HPLC [J].
Akay, C ;
Özkan, SA ;
Sentürk, Z ;
Cevheroglu, S .
FARMACO, 2002, 57 (11) :953-957
[2]   Sensitive assay for the determination of cefazolin or ceftriaxone in plasma utilizing LC [J].
Al-Rawithi, S ;
Hussein, R ;
Raines, DA ;
AlShowaier, I ;
Kurdi, W .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2000, 22 (02) :281-286
[3]   Ultrasensitive Pb2+ detection by glutathione-capped quantum dots [J].
Ali, Emril Mohamed ;
Zheng, Yuangang ;
Yu, Hsiao-hua ;
Ying, Jackie Y. .
ANALYTICAL CHEMISTRY, 2007, 79 (24) :9452-9458
[4]   Luminescent quantum dots for multiplexed biological detection and imaging [J].
Chan, WCW ;
Maxwell, DJ ;
Gao, XH ;
Bailey, RE ;
Han, MY ;
Nie, SM .
CURRENT OPINION IN BIOTECHNOLOGY, 2002, 13 (01) :40-46
[5]   Quantum dot bioconjugates for ultrasensitive nonisotopic detection [J].
Chan, WCW ;
Nie, SM .
SCIENCE, 1998, 281 (5385) :2016-2018
[6]   Ultrasensitive Copper(II) Detection Using Plasmon-Enhanced and Photo-Brightened Luminescence of CdSe Quantum Dots [J].
Chan, Yang-Hsiang ;
Chen, Jixin ;
Liu, Qingsheng ;
Wark, Stacey E. ;
Son, Dong Hee ;
Batteas, James D. .
ANALYTICAL CHEMISTRY, 2010, 82 (09) :3671-3678
[7]   CdSe quantum dots decorated by mercaptosuccinic acid as fluorescence probe for Cu2+ [J].
Chen, Shutang ;
Zhang, Xiaoling ;
Zhang, Qiuhua ;
Hou, Xiaomiao ;
Zhou, Qi ;
Yan, Jilin ;
Tan, Weihong .
JOURNAL OF LUMINESCENCE, 2011, 131 (05) :947-951
[8]   Luminescent CdS quantum dots as selective ion probes [J].
Chen, YF ;
Rosenzweig, Z .
ANALYTICAL CHEMISTRY, 2002, 74 (19) :5132-5138
[9]   Near-infrared Photoluminescent Ag2S Quantum Dots from a Single Source Precursor [J].
Du, Yaping ;
Xu, Bing ;
Fu, Tao ;
Cai, Miao ;
Li, Feng ;
Zhang, Yan ;
Wang, Qiangbin .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (05) :1470-+
[10]   In vivo imaging of quantum dots encapsulated in phospholipid micelles [J].
Dubertret, B ;
Skourides, P ;
Norris, DJ ;
Noireaux, V ;
Brivanlou, AH ;
Libchaber, A .
SCIENCE, 2002, 298 (5599) :1759-1762
12345