Sulfonated xanthones from Hypericum sampsonii

被引：50
|
作者：
Hong, D
Yin, F
Hu, LH
Lu, P
机构：
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
来源：
PHYTOCHEMISTRY | 2004年 / 65卷 / 18期
基金：
中国国家自然科学基金;
关键词：
Hypericum sampsonii; Guttiferae; xanthonoid sulfonates; cytotoxicity;
D O I：
10.1016/j.phytochem.2004.08.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Xanthones, 1,3-dihydroxy-5-methoxyxanthone-4-sulfonate and 1,3-dihydroxy-5-O-beta-D-glycopyranosylxanthone-4-sulfonate, together with nine known compounds were obtained from H. sampsonii. This is the first report of sulfonated xanthonoids. Furthermore, compounds 1 and 2 exhibited significant cytotoxicity against the P388 cancer cell line. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2595 / 2598
页数：4
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