Sulfonated xanthones from Hypericum sampsonii

被引：51

作者：

Hong, D

Yin, F

Hu, LH

Lu, P

机构：

[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

PHYTOCHEMISTRY | 2004年 / 65卷 / 18期

基金：

中国国家自然科学基金;

关键词：

Hypericum sampsonii; Guttiferae; xanthonoid sulfonates; cytotoxicity;

D O I：

10.1016/j.phytochem.2004.08.014

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Xanthones, 1,3-dihydroxy-5-methoxyxanthone-4-sulfonate and 1,3-dihydroxy-5-O-beta-D-glycopyranosylxanthone-4-sulfonate, together with nine known compounds were obtained from H. sampsonii. This is the first report of sulfonated xanthonoids. Furthermore, compounds 1 and 2 exhibited significant cytotoxicity against the P388 cancer cell line. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2595 / 2598

页数：4

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