Th1/Th2 cross-regulation and the discovery of IL-10

被引:37
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D O I
10.1084/jem.2042fta
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In the late 1980s, Tim Mosmann and colleagues isolated functionally distinct T helper (Th)-1 and Th2 clones, and provided evidence that these two subsets were mutually inhibitory. Knowledge of the inhibition led to the discovery that Th2 cells make IL-10 to suppress Th1 cells. © 2007, Rockefeller University Press., All rights reserved.
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页码:237 / 237
页数:1
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