The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects

被引:162
作者
Chapple, CR
Artibani, W
Cardozo, LD
Castro-Diaz, D
Craggs, M
Haab, F
Khullar, V
Versi, E
机构
[1] Univ Sheffield, Royal Hallamshire Hosp, Dept Urol, Sheffield S10 2JF, S Yorkshire, England
[2] Univ Padua, Dept Urol, Padua, Italy
[3] Kings Coll Hosp London, Dept Obstet & Gynaecol, London, England
[4] Univ Canarias, Serv Urol, Tenerife, Spain
[5] UCL Royal Free & Univ Coll Med Sch, Inst Urol, London, England
[6] Hop Tenon, Serv Urol, F-75970 Paris, France
[7] St Marys Hosp, Dept Obstet & Gynaecol, London, England
[8] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Obstet Gynecol & Reprod Sci, New Brunswick, NJ USA
关键词
overactive bladder; urgency; measurement of symptoms; frequency; incontinence;
D O I
10.1111/j.1464-410X.2005.05294.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objective To review the concept of urinary urgency and its practical measurement in clinical trials, and advance the hypothesis that while urge is experienced by normal people, urgency is always pathological. Methods According to the International Continence Society (ICS) definition, urgency is the primary symptom of the overactive bladder (OAB) syndrome, but in clinical trials there are inconsistencies in both the definition and assessment of urgency. We searched the PubMed and BIOSIS databases for publications and abstracts related to the clinical assessment of urgency in patients with OAB. Results The differentiation of urgency from the normal physiological desire to void is discussed. In clinical studies of OAB, urgency has been measured both qualitatively and quantitatively. Existing qualitative assessment scales for urgency are deficient in accuracy, validation or both, and are largely inconsistent with the currently accepted ICS definition of urgency. The quantitative assessment of urgency by diary entry has been validated and may be the most accurate, reproducible and clinically meaningful method available for measuring this variable. Conclusion Based on the existing ICS definition of urgency as 'a compelling desire to pass urine that is difficult to defer', the concept of qualitative assessment of urgency may be flawed.
引用
收藏
页码:335 / 340
页数:6
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