DETERMINING THYMOL AND CARVACROL BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

被引：11

作者：

Alekseeva, L. I. ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Biol, Komi Sci Ctr, Ural Branch, Syktyvkar, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2009年 / 43卷 / 12期

关键词：

thymol and carvacrol; high-performance liquid chromatography; qualitative and quantitative determination; EXTRACTS;

D O I：

10.1007/s11094-010-0377-x

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A reversed-phase high-performance liquid chromatography (RP-HPLC) technique for the qualitative and quantitative determination of carvacrol and thymol in plants and related medicinal preparations has been developed. A chromatographic system consisting of a reversed-phase Diasorb 130-C18T column eluted with a MeOH:H2O:THF (50:50:22, v/v) mixture separates effectively the carvacrol and thymol isomers and ensures their quantitative determination.

引用

页码：665 / 667

页数：3

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