Association between asthma and risk of benign prostatic hyperplasia: a retrospective population-based study

被引:16
作者
Peng, Yi-Hao [1 ,2 ,3 ]
Huang, Chien-Wen [4 ,5 ,6 ]
Chou, Che-Yi [7 ,8 ]
Chiou, Hung-Jie [9 ]
Chen, Hsuan-Ju [10 ,11 ]
Wu, Trong-Neng [12 ]
Ho, Wen-Chao [1 ]
机构
[1] China Med Univ, Dept Publ Hlth, 91 Hsueh Shih Rd, Taichung, Taiwan
[2] Asia Univ, Asia Univ Hosp, Dept Resp Therapy, Taichung, Taiwan
[3] China Med Univ, Dept Resp Therapy, Taichung, Taiwan
[4] Asia Univ Hosp, Dept Internal Med, Div Chest Med, Taichung, Taiwan
[5] Asia Univ, Coll Med & Hlth Sci, Dept Biotechnol, Taichung, Taiwan
[6] Natl Chung Hsing Univ, Coll Life Sci, Inst Mol Biol, Taichung, Taiwan
[7] Asia Univ Hosp, Dept Internal Med, Div Nephrol, Taichung, Taiwan
[8] Asia Univ, Dept Postbaccalaureate Vet Med, Taichung, Taiwan
[9] Asia Univ Hosp, Dept Surg, Div Urol, Taichung, Taiwan
[10] China Med Univ, Coll Med, Taichung, Taiwan
[11] China Med Univ Hosp, Management Off Hlth Data, Taichung, Taiwan
[12] Asia Univ, Dept Hlth Care Adm, Taichung, Taiwan
关键词
Asthma; benign prostatic hyperplasia; cohort study; epidemiology; transurethral resection of the prostate; INFLAMMATION; EXPRESSION; DISEASE; IL-17; BPH;
D O I
10.1080/13685538.2018.1552253
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective The association between asthma and benign prostatic hyperplasia (BPH) has rarely been explored. We investigated whether male asthmatic patients had an increased risk of BPH by conducting this retrospective nationwide population-based study. Methods We utilized data derived from the National Health Insurance Research Database (NHIRD) in Taiwan. A total of 9778 male patients aged >40 years who were newly diagnosed with asthma between 2000 and 2006 were included in the asthma group. Male enrollees without asthma were selected as the non-asthma group from the same database. Both the groups were followed up until the end of 2013. We performed Cox proportional hazard regression analysis to estimate the risk of BPH and transurethral resection of the prostate (TURP) in the male patients with asthma compared with that in those without asthma. Results The risk of BPH and TURP in the asthma group was 1.40-fold (95% confidence interval [CI] = 1.30-1.42) and 1.30-fold (95% CI= 1.31-1.50) higher than that in the non-asthma group, respectively, after adjusting for comorbidities, relevant medications and number of annual outpatient visits. Conclusions The male patients with asthma were found to have a higher risk of BPH than did those without asthma.
引用
收藏
页码:599 / 606
页数:8
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