Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85α) -: Preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women

被引：32

作者：

Baier, LJ ^{[1
]}

Wiedrich, C ^{[1
]}

Hanson, RL ^{[1
]}

Bogardus, C ^{[1
]}

机构：

[1] NIDDKD, Clin Diabet & Nutr Sect, Phoenix Epidemiol & Clin Res Branch, NIH, Phoenix, AZ 85016 USA

来源：

DIABETES | 1998年 / 47卷 / 06期

关键词：

D O I：

10.2337/diabetes.47.6.973

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：973 / 975

页数：3

共 8 条

[1] IDENTIFICATION OF PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE IN PANCREATIC-ISLETS AND INSULIN-SECRETING BETA-CELLS [J].

ALTER, CA ;

WOLF, BA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995, 208 (01) :190-197

[2]

Antonetti DA, 1996, MOL CELL BIOL, V16, P2195

[3] INSULIN RELEASE AND STEROID-HORMONE BINDING IN ISOLATED ISLETS OF LANGERHANS IN THE RAT - EFFECTS OF OVARIECTOMY [J].

ELSEIFI, S ;

GREEN, IC ;

PERRIN, D .

JOURNAL OF ENDOCRINOLOGY, 1981, 90 (01) :59-67

[4] Identification of a common amino acid polymorphism in the p85 alpha regulatory subunit of phosphatidylinositol 3-kinase - Effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index [J].

Hansen, T ;

Andersen, CB ;

Echwald, SM ;

Urhammer, SA ;

Clausen, JO ;

Vestergaard, H ;

Owens, D ;

Hansen, L ;

Pedersen, O .

DIABETES, 1997, 46 (03) :494-501

[5] INSULIN-RESISTANCE AND INSULIN SECRETORY DYSFUNCTION AS PRECURSORS OF NON-INSULIN-DEPENDENT DIABETES-MELLITUS - PROSPECTIVE STUDIES OF PIMA-INDIANS [J].

LILLIOJA, S ;

MOTT, DM ;

SPRAUL, M ;

FERRARO, R ;

FOLEY, JE ;

RAVUSSIN, E ;

KNOWLER, WC ;

BENNETT, PH ;

BOGARDUS, C .

NEW ENGLAND JOURNAL OF MEDICINE, 1993, 329 (27) :1988-1992

[6]

OKADA T, 1994, J BIOL CHEM, V269, P3568

[7]

Report of a WHO Study Group, 1985, WHO TECH REP SER

[8] CLONING OF PI3 KINASE ASSOCIATED P85 UTILIZING A NOVEL METHOD FOR EXPRESSION CLONING OF TARGET PROTEINS FOR RECEPTOR TYROSINE KINASES [J].

SKOLNIK, EY ;

MARGOLIS, B ;

MOHAMMADI, M ;

LOWENSTEIN, E ;

FISCHER, R ;

DREPPS, A ;

ULLRICH, A ;

SCHLESSINGER, J .

CELL, 1991, 65 (01) :83-90

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