Preparation of "Mushroom-like" Janus Particles by Site-Selective Surface-Initiated Atom Transfer Radical Polymerization in Aqueous Dispersed Systems

A versatile approach for the preparation of micrometer-sized, monodisperse, "mushroom-like" Janus polymer particles in aqueous dispersed systems is proposed. The synthetic methodology of the Janus particles consists of the following two steps. The First step is the preparation of spherical poly(methyl methacrylate) (PMMA)/poly(styrene-2-(2-bromoisobutyryloxy)ethyl methacrylate) (P(S-BIEM)) Janus particles based on the internal phase separation induced by solvent evaporation from the solvent droplets dissolving the polymers. The second step is surface-initiated atom transfer radical polymerization (ATRP) of 2-(dimethylamino)ethyl methacrylate (DM) using the Janus particles with ATRP initiator groups at one side of the surface as macroinitiator. As a consequence, mushroom-like PMMA/P(S-BIEM)-graft-poly(DM) Janus particles were prepared, which had pH-responsive property.