A non-invasive microcontroller based estimation of blood glucose concentration by using a modified capacitive sensor at low frequency

被引:7
作者
Dutta, Abhinaba [1 ]
Bera, Satish Chandra [2 ,3 ]
Das, Kamalesh [4 ]
机构
[1] Acad Technol, Dept Elect Engn, PO Aedconagar, Adisaptagram 712121, Hooghly, India
[2] Univ Calcutta, Dept Appl Phys, Instrumentat Engn Sect, 92 APC Rd, Kolkata 700009, India
[3] Techno Main, Kolkata 700091, India
[4] Murshidabad Zillah Parishad, Golapbagh 742149, Murshidabd, India
关键词
D O I
10.1063/1.5116059
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
In the present work, a noninvasive technique of glucose concentration measurement in human blood has been developed. A semicylindrical capacitive sensor is used to measure the blood glucose concentration in terms of capacitance of the sensor. It is shown that this capacitance varies linearly with glucose concentration in human blood. A low frequency operational amplifier based circuit is designed to measure this capacitance in terms of an output voltage signal. A linear relation between the ratio of this output signal to input supply with blood glucose concentration is derived in the paper. A microcontroller based software program is designed to measure this ratio and to display glucose concentration in a LCD display unit in digital form. The performance study of the proposed blood glucose concentration measurement circuit with respect to standard glucometer and that of the proposed blood glucose concentration display unit are carried out in the present work. The experimental results are reported in the paper in both tabular and graphical forms. The linear characteristic graphs and close conformity of the results of the proposed technique with those of standard glucometer are observed. The measurement error with respect to glucometer is found to be within +/- 3.5%. (c) 2019 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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页数:13
相关论文
共 18 条
[1]   Reduction of Blood Glucose Measurements to Calibrate Subcutaneous Glucose Sensors: A Bayesian Multiday Framework [J].
Acciaroli, Giada ;
Vettoretti, Martina ;
Facchinetti, Andrea ;
Sparacino, Giovanni ;
Cobelli, Claudio .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2018, 65 (03) :587-595
[2]  
Chakraborty S., 2015, J. Electr. Bioimpedance, V6, DOI [10.5617/jeb.2363, DOI 10.5617/JEB.2363]
[3]   Noninvasive Continuous Glucose Monitoring Using a Multisensor-Based Glucometer and Time Series Analysis [J].
Geng, Zhanxiao ;
Tang, Fei ;
Ding, Yadong ;
Li, Shuzhe ;
Wang, Xiaohao .
SCIENTIFIC REPORTS, 2017, 7
[4]   The Progress of Glucose MonitoringA Review of Invasive to Minimally and Non-Invasive Techniques, Devices and Sensors [J].
Gonzales, Wilbert Villena ;
Mobashsher, Ahmed Toaha ;
Abbosh, Amin .
SENSORS, 2019, 19 (04)
[5]  
Gourzi M., 2005, Journal of Medical Engineering & Technology, V29, P22, DOI 10.1080/03091900410001720247
[6]   Effective Permittivity of Biological Tissue: Comparison of Theoretical Model and Experiment [J].
Gun, Li ;
Ning, Du ;
Liang, Zhang .
MATHEMATICAL PROBLEMS IN ENGINEERING, 2017, 2017 :1-7
[7]  
Harman-Boehm Ilana, 2010, J Diabetes Sci Technol, V4, P583
[8]   Noninvasive blood glucose monitoring [J].
Klonoff, DC .
DIABETES CARE, 1997, 20 (03) :433-437
[9]   An Approach for Noninvasive Blood Glucose Monitoring Based on Bioimpedance Difference Considering Blood Volume Pulsation [J].
Li, Jingzhen ;
Igbe, Tobore ;
Liu, Yuhang ;
Nie, Zedong ;
Qin, Wenjian ;
Wang, Lei ;
Hao, Yang .
IEEE ACCESS, 2018, 6 :51119-51129
[10]  
Li J, 2017, IEEE ANN INT CONF CY, P1649, DOI 10.1109/CYBER.2017.8446594