Kawasaki Disease Preceding Haemophagocytic Lymphohistiocytosis: Challenges for Developing World Practitioners

被引:16
作者
Hendricks, Marc [1 ]
Pillay, Shakti [2 ]
Davidson, Alan [1 ]
De Decker, Rik [3 ]
Lawrenson, John [4 ]
机构
[1] Univ Cape Town, Red Cross War Mem Childrens Hosp, Paediat Haematol Oncol Serv, ZA-7925 Cape Town, South Africa
[2] Univ Witwatersrand, Victoria Hosp Wynberg, Dept Paediat, Johannesburg, South Africa
[3] Univ Cape Town, Red Cross War Mem Childrens Hosp, Western Cape Paediat Cardiol Serv, ZA-7925 Cape Town, South Africa
[4] Univ Stellenbosch, Red Cross War Mem Childrens Hosp, Dept Paediat & Child Hlth,Tygerberg Childrens Hos, Western Cape Paediat Cardiol Serv, Cape Town, South Africa
关键词
haemophagocytic lymphohistiocytosis; Kawasaki disease; MANIFESTATION;
D O I
10.1002/pbc.22422
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Kawasaki disease (KD) is a recognised precipitant of haemophagocytic lymphohistiocytosis (HLH). Although KD has been previously described in the developing world, there are no reported cases of KD preceding HLH. We report a case of a child with a persistent rash and unremitting fever consistent with the diagnosis of KID, who was found to have HLH, after intravenous gamma globulin failed to produce a clinical response. The diagnosis was made using the revised diagnostic criteria for HLH from the Histiocyte Society (1994). She fulfilled six of the eight clinical and laboratory criteria needed to make the diagnosis. Pediatr Blood Cancer 2010;54:1023-1025. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码:1023 / 1025
页数:3
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