Targeted ultraviolet B phototherapy: definition, clinical indications and limitations

被引:8
作者
Alshiyab, D. [1 ]
Edwards, C. [2 ]
Chin, M. F. [3 ]
Anstey, A. V. [2 ,4 ]
机构
[1] Jordan Univ Sci & Technol, Dept Dermatol, Fac Med, Irbid, Jordan
[2] St Woolos Hosp, Acad Dermatol Unit, Newport NP20 4SZ, Gwent, Wales
[3] Univ Wales Hosp, Dept Dermatol, Cardiff CF4 4XW, S Glam, Wales
[4] Cardiff Univ, Cardiff CF10 3AX, S Glam, Wales
关键词
308-NM EXCIMER-LASER; PLAQUE-TYPE PSORIASIS; UVB PHOTOTHERAPY; LOCALIZED VITILIGO; LIGHT; REPIGMENTATION; COMBINATION; RADIATION; EFFICACY; THERAPY;
D O I
10.1111/ced.12441
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Targeted ultraviolet B (UVB) phototherapy is defined as UVB radiation applied only to clinically diseased skin, with sparing of adjacent normal skin, unlike conventional phototherapy, which involves irradiation of both diseased and normal skin. Targeted UVB radiation is a relatively new concept, which is now widely available because of advances in technology. Devices developed for targeted UVB phototherapy of the skin include the monochromatic excimer laser and lamp, both of which are now used by dermatologists in developed and developing countries. The aim of this review is to collate data from research studies on targeted phototherapy and to provide a concise description of currently available devices, their clinical indications and therapeutic efficacy. Additionally, potential adverse effects are summarized, and the limitations of these novel devices are highlighted. Click for the corresponding questions to this CME article.
引用
收藏
页码:1 / 5
页数:5
相关论文
共 30 条
[1]   Broadband targeted UVB phototherapy for localized vitiligo: a retrospective study [J].
Akar, Ahmet ;
Tunca, Mustafa ;
Koc, Erol ;
Kurumlu, Zafer .
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 2009, 25 (03) :161-163
[2]   Targeted phototherapy using 308 nm Xecl monochromatic excimer laser for psoriasis at difficult to treat sites [J].
Al-Mutairi, Nawaf ;
Al-Haddad, Ahmad .
LASERS IN MEDICAL SCIENCE, 2013, 28 (04) :1119-1124
[3]   8-methoxypsoralen cream plus targeted narrowband ultraviolet B for psoriasis [J].
Amornpinyokeit, Noppadol ;
Asawanonda, Pravit .
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 2006, 22 (06) :285-289
[4]   Targeted broadband ultraviolet B phototherapy produces similar responses to targeted narrowband ultraviolet B phototherapy for vitiligo: A randomized, double-blind study [J].
Asawanonda, Pravit ;
Kijluakiat, Jirasin ;
Korkij, Wiwat ;
Sindhupak, Wannasri .
ACTA DERMATO-VENEREOLOGICA, 2008, 88 (04) :376-381
[5]   Treatment of localized vitiligo with targeted broadband UVB phototherapy: a pilot study [J].
Asawanonda, Pravit ;
Charoenlap, Marisa ;
Korkij, Wiwat .
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 2006, 22 (03) :133-136
[6]   Evaluation of a novel 308-nm monochromatic excimer light delivery system in dermatology: a pilot study in different chronic localized dermatoses [J].
Aubin, F ;
Vigan, M ;
Puzenat, E ;
Blanc, D ;
Drobacheff, C ;
Deprez, P ;
Humbert, P ;
Laurent, R .
BRITISH JOURNAL OF DERMATOLOGY, 2005, 152 (01) :99-103
[7]   Repigmentation of localized vitiligo with the xenon chloride [J].
Baltás, E ;
Nagy, P ;
Bónis, B ;
Novák, Z ;
Ignácz, F ;
Szabó, G ;
Bor, Z ;
Dobozy, A ;
Kemény, L .
BRITISH JOURNAL OF DERMATOLOGY, 2001, 144 (06) :1266-1267
[8]  
Chimento SM, 2008, J DRUGS DERMATOL, V7, P258
[9]   ROLE OF HAIR-FOLLICLES IN THE REPIGMENTATION OF VITILIGO [J].
CUI, J ;
SHEN, LY ;
WANG, GC .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1991, 97 (03) :410-416
[10]   Ultraviolet B 308-nm excimer laser treatment of psoriasis: a new phototherapeutic approach [J].
Gerber, W ;
Arheilger, B ;
Ha, TA ;
Hermann, J ;
Ockenfels, HM .
BRITISH JOURNAL OF DERMATOLOGY, 2003, 149 (06) :1250-1258