Harmonization in autoimmune thyroid disease diagnostics

被引:7
作者
Tozzoli, Renato [3 ]
Bizzaro, Nicola [1 ,2 ]
机构
[1] Via ML King 25, I-30027 Venice, Italy
[2] San Antonio Hosp, Lab Clin Pathol, Tolmezzo, Italy
[3] S Maria degli Angeli Hosp, Lab Clin Pathol, Pordenone, Italy
关键词
autoimmune thyroid disease; Graves' disease; harmonization; Hashimoto's thyroiditis; thyroglobulin antibodies; thyroperoxidase antibodies; TSH-receptor antibodies; UPPER REFERENCE LIMIT; PEROXIDASE AUTOANTIBODIES; LABORATORY MEDICINE; TSH; STANDARDIZATION; IMMUNOASSAY; MULTICENTER; GUIDELINES; ANTIBODIES;
D O I
10.1515/cclm-2018-0037
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
In this review we analyze all aspects of total testing process regarding the measurement of antithyroid peroxidase, antithyroglobulin and antithyrotropin receptor autoantibodies. The main critical points related to the preanalytical, analytical and postanalytical steps of autoimmune thyroid disease diagnostics are considered, focusing on harmonization of autoimmune thyroid tests request, retesting intervals, terminology of thyroid autoantibodies, measurement units and definition of reference limits. Harmonization in thyroid autoantibody testing is a relevant example of feasible harmonization in autoimmunology.
引用
收藏
页码:1778 / 1782
页数:5
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