Colorimetric detection of influenza A (H1N1) virus by a peptide-functionalized polydiacetylene (PEP-PDA) nanosensor

被引：45
作者：
Song, Sinae [1 ]
Ha, Kab [1 ]
Guk, Kyeonghye [1 ,3 ]
Hwang, Seul-Gee [1 ,3 ]
Choi, Jong Min [2 ]
Kang, Taejoon [1 ,3 ]
Bae, Pankee [2 ]
Jung, Juyeon [1 ,3 ]
Lim, Eun-Kyung [1 ]
机构：
[1] Korea Res Inst Biosci & Biotechnol, Hazards Monitoring BioNano Res Ctr, Daejeon 305806, South Korea
[2] Korea Res Inst Biosci & Biotechnol, BioNano Hlth Guard Res Ctr, Daejeon 305806, South Korea
[3] Univ Sci & Technol, Sch Engn, Major Nanobiotechnol & Bioinformat, 217 Gajeong Ro, Daejeon 305350, South Korea
来源：
RSC ADVANCES | 2016年 / 6卷 / 54期
基金：
新加坡国家研究基金会;
关键词：
REVERSIBLE THERMOCHROMISM; OXIDE NANOCOMPOSITES; PROTEIN; VESICLES; LIPOSOME; BEACONS; APTAMER; ANTIGEN; COLOR; ASSAY;
D O I：
10.1039/c6ra06689e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We developed a peptide-functionalized polydiacetylene (PEP-PDA) nanosensor for pandemic H1N1 virus (pH1N1) detection with the naked eye. A PDA nanosensor was fabricated by nano-precipitation and modified with PEP for the specific recognition of pH1N1. The PEP-PDA nanosensor showed unique chromatic properties involving a colour change fromblue to red in the presence of pH1N1. We believe that this nanosensor can be applied for the development of a commercially available kit for pH1N1 detection.
引用
收藏
页码：48566 / 48570
页数：5
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