Periodontal regeneration with 0.3 % basic fibroblast growth factor (FGF-2) for a patient with aggressive periodontitis: a case report

被引：5
作者：
Yoshinuma, Naoto [1 ,2 ]
Koshi, Ryosuke [1 ,2 ]
Kawamoto, Kazuhiro [1 ]
Idesawa, Masataka [3 ]
Sugano, Naoyuki [1 ,2 ]
Sato, Shuichi [1 ,2 ]
机构：
[1] Nihon Univ, Sch Dent, Dept Periodontol, Tokyo 1018310, Japan
[2] Nihon Univ, Sch Dent, Dent Res Ctr, Div Adv Dent Treatment, Tokyo 1018310, Japan
[3] Shunyokai Sakura Dent Off, Chiba, Japan
来源：
JOURNAL OF ORAL SCIENCE | 2016年 / 58卷 / 01期
关键词：
FGF-2; periodontal regeneration; aggressive periodontitis; clinical trial; TISSUE REGENERATION; DEFECTS; THERAPY; BFGF;
D O I：
10.2334/josnusd.58.137
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
This case report describes the clinical efficacy of treatment with basic fibroblast growth factor (FGF-2) for periodontal regeneration. A patient with aggressive periodontitis participated in a clinical trial involving administration of 0.3% FGF-2 in comparison with a placebo control. To evaluate the efficacy of FGF-2, standardized radiographs were taken before surgery and at 12, 24, and 36 weeks after FGF-2 treatment. The rate of increase in alveolar bone height was 86.9% at 36 weeks. The 6-year postoperative radiograph showed significant development of alveolar bone in comparison with the first visit. FGF-2 treatment may be effective for periodontal regeneration in cases of aggressive periodontitis.
引用
收藏
页码：137 / 140
页数：4
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