Periodontal regeneration with 0.3 % basic fibroblast growth factor (FGF-2) for a patient with aggressive periodontitis: a case report

被引：5

作者：

Yoshinuma, Naoto ^{[1
,2
]}

Koshi, Ryosuke ^{[1
,2
]}

Kawamoto, Kazuhiro ^{[1
]}

Idesawa, Masataka ^{[3
]}

Sugano, Naoyuki ^{[1
,2
]}

Sato, Shuichi ^{[1
,2
]}

机构：

[1] Nihon Univ, Sch Dent, Dept Periodontol, Tokyo 1018310, Japan

[2] Nihon Univ, Sch Dent, Dent Res Ctr, Div Adv Dent Treatment, Tokyo 1018310, Japan

[3] Shunyokai Sakura Dent Off, Chiba, Japan

来源：

JOURNAL OF ORAL SCIENCE | 2016年 / 58卷 / 01期

关键词：

FGF-2; periodontal regeneration; aggressive periodontitis; clinical trial; TISSUE REGENERATION; DEFECTS; THERAPY; BFGF;

D O I：

10.2334/josnusd.58.137

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

This case report describes the clinical efficacy of treatment with basic fibroblast growth factor (FGF-2) for periodontal regeneration. A patient with aggressive periodontitis participated in a clinical trial involving administration of 0.3% FGF-2 in comparison with a placebo control. To evaluate the efficacy of FGF-2, standardized radiographs were taken before surgery and at 12, 24, and 36 weeks after FGF-2 treatment. The rate of increase in alveolar bone height was 86.9% at 36 weeks. The 6-year postoperative radiograph showed significant development of alveolar bone in comparison with the first visit. FGF-2 treatment may be effective for periodontal regeneration in cases of aggressive periodontitis.

引用

页码：137 / 140

页数：4

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