Ceftriaxone-induced Hemolytic Anemia: Case Report and Review of Literature

被引：18

作者：

Northrop, Michael S. ^{[1
]}

Agarwal, Hemant S. ^{[1
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Pediat, Nashville, TN 37232 USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2015年 / 37卷 / 01期

关键词：

ceftriaxone; immune hemolytic anemia; acute renal failure; multiple organ failure; drug induced; SICKLE-CELL-DISEASE; IMMUNODEFICIENCY-VIRUS-INFECTION; ACUTE-RENAL-FAILURE; FATAL HEMOLYSIS; PEDIATRIC-PATIENTS; IMMUNE HEMOLYSIS; CHILD; ANTIBODIES; ISCHEMIA; THERAPY;

D O I：

10.1097/MPH.0000000000000181

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Ceftriaxone is a frequently used empiric antibiotic in children. Acute hemolysis is a rare side effect of ceftriaxone therapy associated with a high mortality rate. A 14-year-old boy suffering from Crohn disease developed bacterial pneumonia that was treated with ceftriaxone. We report successful management of ceftriaxone-induced hemolytic anemia (CIHA) in this patient and review the CIHA literature in pediatric patients. Early recognition of CIHA with prompt discontinuation of ceftriaxone therapy may have a beneficial role in reduction of high mortality seen in these patients.

引用

页码：E63 / E66

页数：4

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