Bone tissue engineering: Adult stem cells in combination with electrospun nanofibrous scaffolds

被引:73
作者
Moradi, Sadegh L. [1 ]
Golchin, Ali [1 ]
Hajishafieeha, Zahra [2 ]
Khani, Mohammad-Mehdi [1 ]
Ardeshirylajimi, Abdolreza [1 ,3 ]
机构
[1] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Tissue Engn & Appl Cell Sci, Tehran, Iran
[2] Qazvin Univ Med Sci, Dept Microbiol, Qazvin, Iran
[3] St Louis Univ, Sch Med, Edward A Doisy Dept Biochem & Mol Biol, St Louis, MO USA
关键词
bone tissue engineering; fabrication; natural biopolymers; regenerative medicine and adult stem cells; synthetic biopolymers; MESENCHYMAL STROMAL CELLS; OSTEOGENIC DIFFERENTIATION; IN-VITRO; SIGNALING PATHWAYS; CELLULOSE-ACETATE; FABRICATION; MARROW; CHITOSAN; BIOMATERIALS; RECONSTRUCTION;
D O I
10.1002/jcp.26606
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Since bone tissue lesions caused by several reasons and has global outbreak without any attentions to the modernity level of the countries. In the other hands treatment of patients with this problem faced to the several limitations, in this because the future of the bone lesions treatments is related to the future of the bone tissue engineering. This review tries to cover the most suitable stem cells and materials from either natural or synthetic sources for bone tissue engineering. These understanding points would help researchers to further uncover the application of different adult stem cell sources in electrospinning scaffolds, promotion of nanofibrous composite construct design and adult stem cell type selection to enhance cell function and bone tissue engineering, and link laboratory investigations to clinical applications.
引用
收藏
页码:6509 / 6522
页数:14
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