LDL-Cholesterol Is Not the Only Clinically Relevant Biomarker for Coronary Artery Disease or Acute Coronary Syndrome

被引：10

作者：

Field, Patrick A. ^{[1
,2
]}

Vasan, Ramachandran S. ^{[1
,2
,3
,4
,5
,6
]}

机构：

[1] Boston Univ, Boston, MA 02215 USA

[2] NHLBI, Framingham Study, Framingham, MA USA

[3] Boston Univ, Sch Med, Sect Prevent Med & Epidemiol, Dept Epidemiol, Boston, MA 02118 USA

[4] Boston Univ, Sch Med, Sect Cardiovasc Med, Dept Epidemiol, Boston, MA 02118 USA

[5] Boston Univ, Sch Publ Hlth, Sect Prevent Med & Epidemiol, Dept Epidemiol, Boston, MA 02118 USA

[6] Boston Univ, Sch Publ Hlth, Sect Cardiovasc Med, Dept Epidemiol, Boston, MA 02118 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2018年 / 104卷 / 02期

关键词：

CARDIOVASCULAR RISK;

D O I：

10.1002/cpt.1126

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Coronary artery disease (CAD) is a progressive disorder and its risk is best determined using multiple biomarkers and risk factors. Many novel biomarkers have been shown to improve cardiovascular disease risk beyond that of the traditional risk factors, including polygenic risk scores, small very low-density lipoprotein (VLDL), ApoB, triglycerides (TG), non-HDL-c, lipoprotein (a) (Lp(a)), coronary calcium scores, C-reactive protein (CRP), B-type natriuretic peptide (BNP), troponins, and many other novel biomarkers that have been measured using high throughput assays.

引用

页码：232 / 234

页数：3

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