Tunable Synthesis of 1,2,3-Triazoles and Enamines through Deacylative Azide-Alkene Cycloaddition

被引：6

作者：

Rengasamy, R. ^{[1
,2
]}

Raj, J. Paul ^{[3
]}

Vijayalakshmi, K. ^{[1
,2
]}

Punitha, N. ^{[1
,2
]}

Kesavan, M. ^{[4
]}

Vajjiravel, M. ^{[3
]}

Elangovan, Jebamalai ^{[1
,2
]}

机构：

[1] Rajah Serf Govt Coll, PG & Res Dept Chem, Thanjavur, India

[2] Bharathidasan Univ, Tiruchirappalli 613005 24, Tamil Nadu, India

[3] BS Abdur Rahman Crescent Inst Sci & Technol, Dept Chem, Chennai 600048, Tamil Nadu, India

[4] SRM Inst Sci & Technol, Interdisplinary Inst Indian Syst Med IIISM, Kattankulathur 603203, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 2022卷 / 16期

关键词：

Azide-alkene cycloaddition; Cycloaddition; Deacylative azide-alkene cycloaddition; Nitrogen heterocycles; 1; 2; 3-Triazoles; RUTHENIUM-CATALYZED CYCLOADDITION; REGIOSELECTIVE SYNTHESIS; CLICK CHEMISTRY; 1,3-DIPOLAR CYCLOADDITIONS; ALKYNE CYCLOADDITION; ORGANIC AZIDES; COPPER; SCOPE; TRANSANNULATION; TRIAZOLES;

D O I：

10.1002/ejoc.202101470

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A tunable synthesis of 1,4,5-trisubstituted 1,2,3-triazoles and enamines through [3+2] cycloaddition of activated olefins and organic azides is reported. Triazoles were achieved from benzylidene diketones and organic azides by copper oxide nanoparticle catalysis while enamines were synthesized from benzylidene malonates and organic azides under solvent-free and catalyst-free condition.

引用

页数：5

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