Can the SARS-CoV-2 Omicron Variant Confer Natural Immunity against COVID-19?

被引:15
作者
Abas, Abdul Hawil [1 ]
Marfuah, Siti [1 ]
Idroes, Rinaldi [2 ]
Kusumawaty, Diah [3 ]
Fatimawali [4 ]
Park, Moon Nyeo [5 ]
Siyadatpanah, Abolghasem [6 ]
Alhumaydhi, Fahad A. [7 ]
Mahmud, Shafi [8 ]
Tallei, Trina Ekawati [1 ]
Bin Emran, Talha [9 ]
Kim, Bonglee [5 ]
机构
[1] Sam Ratulangi Univ, Fac Math & Nat Sci, Dept Biol, Manado 95115, North Sulawesi, Indonesia
[2] Univ Syiah Kuala, Fac Math & Nat Sci, Dept Pharm, Banda Aceh 23111, Aceh, Indonesia
[3] Univ Pendidikan Indonesia, Fac Math & Nat Sci Educ, Dept Biol, Bandung 40154, West Java, Indonesia
[4] Sam Ratulangi Univ, Fac Math & Nat Sci, Pharm Study Program, Manado 95115, North Sulawesi, Indonesia
[5] Kyung Hee Univ, Coll Korean Med, Seoul 05253, South Korea
[6] Birjand Univ Med Sci, Ferdows Sch Paramed & Hlth, Birjand 9717853577, Iran
[7] Qassim Univ, Coll Appl Med Sci, Dept Med Labs, Buraydah 52571, Saudi Arabia
[8] Australian Natl Univ, John Curtin Sch Med Res, Dept Genome Sci, Canberra, ACT 0200, Australia
[9] BGC Trust Univ Bangladesh, Dept Pharm, Chittagong 4381, Bangladesh
基金
新加坡国家研究基金会;
关键词
COVID-19; SARS-CoV-2; Omicron; natural immunity; hybrid immunity; MAIN PROTEASE; TRANSMISSION; MECHANISMS; INFECTION; VACCINES; FUTURE; ORIGIN;
D O I
10.3390/molecules27072221
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The coronavirus disease 2019 (COVID-19) pandemic is still ongoing, with no signs of abatement in sight. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of this pandemic and has claimed over 5 million lives, is still mutating, resulting in numerous variants. One of the newest variants is Omicron, which shows an increase in its transmissibility, but also reportedly reduces hospitalization rates and shows milder symptoms, such as in those who have been vaccinated. As a result, many believe that Omicron provides a natural vaccination, which is the first step toward ending the COVID-19 pandemic. Based on published research and scientific evidence, we review and discuss how the end of this pandemic is predicted to occur as a result of Omicron variants being surpassed in the community. In light of the findings of our research, we believe that it is most likely true that the Omicron variant is a natural way of vaccinating the masses and slowing the spread of this deadly pandemic. While the mutation that causes the Omicron variant is encouraging, subsequent mutations do not guarantee that the disease it causes will be less severe. As the virus continues to evolve, humans must constantly adapt by increasing their immunity through vaccination.
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页数:19
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