Percutaneous Sclerotherapy for Facial Venous Malformations: Subjective Clinical and Objective MR Imaging Follow-Up Results

被引:48
作者
Spence, J. [1 ]
Krings, T. [1 ]
terBrugge, K. G. [1 ]
da Costa, L. B. [1 ]
Agid, R. [1 ]
机构
[1] Toronto Western Hosp, Dept Med Imaging, Div Neuroradiol, Toronto, ON M5T 2S8, Canada
关键词
VASCULAR MALFORMATIONS; THERAPEUTIC ISSUES; PEDIATRIC-PATIENTS; CLASSIFICATION; PINGYANGMYCIN; HEMANGIOMAS; INJECTION;
D O I
10.3174/ajnr.A1940
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND AND PURPOSE. Venous malformations are the most common of all vascular anomalies, 40% of which are found in the head and neck We discuss results of percutaneous sclerotherapy using bleomycin for facial VMs by using subjective clinical assessment and objective changes on MR imaging MATERIALS AND METHODS Thirty-seven patients with facial VMs were treated by percutaneous sclerotherapy with bleomycin Of these, 31 patients with 32 lesions had pre- and posttreatment MR imaging Each lesion received between 1 and 9 sclerotherapy sessions (average, 3 5) MR findings and clinical results of treatment were retrospectively reviewed Clinical results were based on the physician's physical examination and interview of the patient, these were classified as worse, unchanged, or better Objective results on MR imaging were classified as worse, no change, minor improvement (<50% decrease in size), marked improvement (>= 50% decrease), or cure Objective and subjective results were compared RESULTS Twenty-one lesions showed objective improvement on MR imaging Of these, 10 showed minor decrease in size and 11 showed marked decrease Eleven lesions showed no change on MR imaging No VMs were worse or completely cured Subjectively, 29 patients and 30 clinicians thought that lesions improved Four of 32 (12 5%) patients suffered minor transient complications CONCLUSIONS Percutaneous sclerotherapy by using bleomycin is a safe technique to objectively decrease size and subjectively alleviate symptoms of facial VMs Subjective clinical improvement is not always associated with visual size reduction on MR imaging Minimal size reduction or partial fibrosis of the lesion may be enough to achieve subjective clinical improvement
引用
收藏
页码:955 / 960
页数:6
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