Metastatic cancer of unknown primary in 21 dogs

被引：21

作者：

Rossi, F. ^{[1
]}

Aresu, L. ^{[2
]}

Vignoli, M. ^{[1
]}

Buracco, P. ^{[3
]}

Bettini, G. ^{[4
]}

Ferro, S. ^{[2
]}

Gattino, F. ^{[3
]}

Ghiani, F. ^{[5
]}

Costantino, R. ^{[6
]}

Ressel, L. ^{[7
]}

Bellei, E. ^{[8
]}

Marconato, L. ^{[1
]}

机构：

[1] Ctr Oncol Vet, Sasso Marconi, Italy

[2] Univ Padua, Dept Comparat Biomed & Nutr, Legnaro, Italy

[3] Sch Vet, Dept Anim Pathol, Grugliasco, Italy

[4] Univ Bologna, Dept Vet Med Sci, Bologna, Italy

[5] Studio Vet Associato Costa Ghiani Spallarossa, Genoa, Italy

[6] Clin Vet Orob, Bergamo, Italy

[7] Diagnost Vet Lab, Sasso Marconi, Italy

[8] Ctr Med Vet, Finale Emilia, Italy

来源：

VETERINARY AND COMPARATIVE ONCOLOGY | 2015年 / 13卷 / 01期

关键词：

carcinoma; dog; MCUP; metastatic cancer; prognosis; COOPERATIVE-ONCOLOGY-GROUP; PRIMARY SITE; PRIMARY ORIGIN; PRIMARY-CARCINOMA; TUMORS; MELANOMA; MALIGNANCY; DIAGNOSIS;

D O I：

10.1111/vco.12011

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The aim of this retrospective study was to describe clinical features, treatment and outcome of 21 dogs with metastatic cancer of unknown primary (MCUP), a biopsy-proven malignancy being diagnosed at a metastatic stage, in which the anatomical origin of the primary tumour cannot be detected. All dogs underwent total-body computed tomography. Signalment, type and duration of clinical signs, metastasis site, pathology results, treatment and outcome were recorded. Carcinoma was the most common diagnosis (57.1%), followed by sarcoma, melanoma and mast cell tumour. The median number of disease sites per dog was 2, with bones, lymph nodes, lungs and spleen being the most frequent metastatic locations. The median survival for all dogs was 30days. Overall, a primary site was not identified in 20 (95.2%) dogs. MCUP encompasses a variety of different pathologic entities and harbours a poor prognosis.

引用

页码：11 / 19

页数：9

共 30 条

[21] Cancer of unknown primary: biological and clinical characteristics [J].