Dietary mannan oligosaccharide ameliorates cyclic heat stress-induced damages on intestinal oxidative status and barrier integrity of broilers

被引：118

作者：

Cheng, Y. F. ^{[1
]}

Chen, Y. P. ^{[1
]}

Chen, R. ^{[1
]}

Su, Y. ^{[1
]}

Zhang, R. Q. ^{[1
]}

He, Q. F. ^{[1
]}

Wang, K. ^{[1
]}

Wen, C. ^{[1
]}

Zhou, Y. M. ^{[1
]}

机构：

[1] Nanjing Agr Univ, Coll Anim Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China

来源：

POULTRY SCIENCE | 2019年 / 98卷 / 10期

关键词：

mannan oligosaccharide; cyclic heat stress; antioxidant capacity; intestinal barrier function; broiler; GROWTH-PERFORMANCE; PHYSIOLOGICAL-RESPONSES; MICROBIAL-POPULATIONS; ANTIOXIDANT CAPACITY; INDUCED IMPAIRMENT; PROBIOTIC MIXTURE; GENE-EXPRESSION; MEAT QUALITY; BEE POLLEN; SUPPLEMENTATION;

D O I：

10.3382/ps/pez192

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

This study investigated protective effects of mannan oligosaccharide (MOS) inclusion on growth performance, intestinal oxidative status, and barrier integrity of cyclic heat-stressed broilers. A total of 240 one-day-old chicks were allocated into 3 treatments of 10 replicates each. Control broilers reared at a thermoneutral temperature were fed a basal diet, whereas broilers in heat stress and MOS groups raised at a cyclic high temperature (32 to 33 degrees C for 8 h/d) were given the basal diet supplemented with 0 or 250 mg/kg MOS, respectively. Compared with control group, heat stress decreased (P < 0.05) average daily gain and feed conversion ratio during grower, finisher, and entire periods, average daily feed intake during finisher and entire periods, and ileal superoxide dismutase activity at 42 D, whereas increased (P < 0.05) rectal temperature at 21 and 42 D and jejunal malondialdehyde content at 42 D. Dietary MOS increased (P < 0.05) average daily gain, average daily feed intake, and feed conversion ratio during finisher and entire periods, but decreased (P < 0.05) jejunal malondialdehyde concentration of heat-stressed broilers at 42 D. Heat stress decreased (P < 0.05) jejunal villus height (VH) and claudin-3 gene expression at 21 D, and VH and VH: crypt depth (CD) ratio in jejunum and ileum as well as mRNA abundances of jejunal mucin 2 and occludin, and ileal mucin 2, zonula occludens-1, and occludin, and claudin-3 at 42 D, whereas increased (P < 0.05) serum D-lactate acid content at 21 and 42 D, and serum diamine oxidase activity and jejunal CD at 42 D. The MOS supplementation increased (P < 0.05) jejunal VH at 21 D, VH and VH: CD of jejunum and ileum at 42 D, mRNA abundances of jejunal occludin and ileal mucin 2, zonula occludens-1, and occludin at 42 D, whereas reduced (P < 0.05) ileal CD at 42 D. These results suggested that MOS improved growth performance, and oxidative status and barrier integrity in the intestine of broilers under cyclic heat stress.

引用

页码：4767 / 4776

页数：10

共 68 条

[1] Effect of potassium chloride supplementation in drinking water on broiler performance under heat stress conditions [J].

Ahmad, T. ;

Khalid, T. ;

Mushtaq, T. ;

Mirza, M. A. ;

Nadeem, A. ;

Babar, M. E. ;

Ahmad, G. .

POULTRY SCIENCE, 2008, 87 (07) :1276-1280

[2] Effect of dietary supplementation of prebiotics and probiotics on intestinal microarchitecture in broilers reared under cyclic heat stress [J].

Ashraf, S. ;

Zaneb, H. ;

Yousaf, M. S. ;

Ijaz, A. ;

Sohail, M. U. ;

Muti, S. ;

Usman, M. M. ;

Ijaz, S. ;

Rehman, H. .

JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2013, 97 :68-73

[3] Blood Hematological and Biochemical Constituents, Antioxidant Enzymes, Immunity and Lymphoid Organs of Broiler Chicks Supplemented with Propolis, Bee Pollen and Mannan Oligosaccharides Continuously or Intermittently [J].

Attia, Y. A. ;

Al-Khalaifah, H. ;

Ibrahim, M. S. ;

Abd Al-Hamid, A. E. ;

Al-Harthi, M. A. ;

El-Naggar, A. .

POULTRY SCIENCE, 2017, 96 (12) :4182-4192

[4] Productive performance, biochemical and hematological traits of broiler chickens supplemented with propolis, bee pollen, and mannan oligosaccharides continuously or intermittently [J].

Attia, Y. A. ;

Al-Hamid, A. E. Abd ;

Ibrahim, M. S. ;

Al-Harthi, M. A. ;

Bovera, F. ;

Elnaggar, A. Sh. .

LIVESTOCK SCIENCE, 2014, 164 :87-95

[5] Effect of ascorbic acid or increasing metabolizable energy level with or without supplementation of some essential amino acids on productive and physiological traits of slow-growing chicks exposed to chronic heat stress [J].

Attia, Y. A. ;

Hassan, R. A. ;

El-Din, A. E. Tag ;

Abou-Shehema, B. M. .

JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2011, 95 (06) :744-755

[6] Effects of purified lignin and mannan oligosaccharides on intestinal integrity and microbial populations in the ceca and litter of broiler chickens [J].

Baurhoo, B. ;

Phillip, L. ;

Ruiz-Feria, C. A. .

POULTRY SCIENCE, 2007, 86 (06) :1070-1078

[7] Effects of diets containing different concentrations of mannanoligosaccharide or antibiotics on growth performance, intestinal development, cecal and litter microbial populations, and carcass parameters of broilers [J].

Baurhoo, B. ;

Ferket, P. R. ;

Zhao, X. .

POULTRY SCIENCE, 2009, 88 (11) :2262-2272

[8] Effects of dietary mannan oligosaccharide and herbal essential oil blend supplementation on performance and oxidative stability of eggs and liver in laying hens [J].

Bozkurt, Mehmet ;

Tokusoglu, Ozlem ;

Kucukyilmaz, Kamil ;

Aksit, Hasan ;

Cabuk, Metin ;

Catli, Abdullah Ugur ;

Seyrek, Kamil ;

Cinar, Mustafa .

ITALIAN JOURNAL OF ANIMAL SCIENCE, 2012, 11 (02) :223-229

[9] Salmosan, a β-Galactomannan-Rich Product, Protects Epithelial Barrier Function in Caco-2 Cells Infected by Salmonella enterica Serovar Enteritidis [J].

Brufau, M. Teresa ;

Campo-Sabariz, Joan ;

Bou, Ricard ;

Carne, Sergi ;

Brufau, Joaquim ;

Vila, Borja ;

Marques, Ana M. ;

Guardiola, Francesc ;

Ferrer, Ruth ;

Martin-Venegas, Raquel .

JOURNAL OF NUTRITION, 2016, 146 (08) :1492-1498

[10] Mannan oligosaccharide increases serum concentrations of antibodies and inflammatory mediators in weanling pigs experimentally infected with porcine reproductive and respiratory syndrome virus [J].

Che, T. M. ;

Song, M. ;

Liu, Y. ;

Johnson, R. W. ;

Kelley, K. W. ;

Van Alstine, W. G. ;

Dawson, K. A. ;

Pettigrew, J. E. .

JOURNAL OF ANIMAL SCIENCE, 2012, 90 (08) :2784-2793

← 1 2 3 4 5 6 7 →