Synthesis of N-substituted 1,2,5-thiadiazolidine and 1,2,6-thiadiazinane 1,1-dioxides from primary amines

被引：9

作者：

Johnson, PD ^{[1
]}

Jewell, SA

Romero, DL

机构：

[1] Pharmacia, Med Chem, Kalamazoo, MI 49001 USA

[2] Alma Coll, Alma, MI 48801 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 29期

关键词：

D O I：

10.1016/S0040-4039(03)01269-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkyl and aryl N-substituted 1,2,5-thiadiazolidine and 1,2,6-thiadiazinane 1,1-dioxides 6 were synthesized in good yields from the reaction of sulfuryl chloride with 2-chloroethylamine or 3-chloropropylamine hydrochlorides, respectively, followed by treatment with a primary amine and triethylamine, and ring closure with K2CO3 in DMSO. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：5483 / 5485

页数：3

共 5 条

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