Adjuvant Endocrine Therapy for Breast Cancer During Perimenopause

被引：1
|
作者：
Noss, D. [1 ]
Buchholz, S. [1 ]
Ortmann, O. [1 ]
机构：
[1] Univ Regensburg, Klin Frauenheilkunde & Geburtshilfe, D-93053 Regensburg, Germany
来源：
GEBURTSHILFE UND FRAUENHEILKUNDE | 2010年 / 70卷 / 02期
关键词：
perimenopause; breast cancer; endocrine therapy; menopausal status; PREMENOPAUSAL WOMEN; AROMATASE INHIBITORS; HORMONE; CHEMOTHERAPY; METAANALYSIS; TAMOXIFEN;
D O I：
10.1055/s-0029-1240825
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Adjuvant endocrine treatment plays an important role in the treatment of estrogen responsive breast cancer. The treatment options for premenopausal women differ from those for postmenopausal women. Aromatase inhibitors (AI) improve the outcomes in postmenopausal women, while AI can induce an increase in estrogen secretion and tumor growth in premenopausal women. The standard therapy during premenopause remains tamoxifen with or without ovarian suppression by GnRH analogues. Treatment of perimenopausal breast cancer patients can be more complicated, because it is often difficult to determine menopausal status.
引用
收藏
页码：112 / 116
页数：5
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