Effects of opioid-reduced anesthesia during scoliosis surgery in children: a prospective observational study

被引：16
作者：
Julien-Marsollier, Florence [1 ,2 ,3 ]
Assaker, Rita [1 ,2 ,3 ]
Michelet, Daphne [1 ,2 ,3 ]
Camby, Matthieu [1 ,2 ,3 ]
Galland, Anne [1 ,2 ,3 ]
Marsac, Lucile [1 ,2 ,3 ]
Vacher, Thomas [1 ,2 ,3 ]
Simon, Anne-laure [1 ,4 ]
Ilharreborde, Brice [1 ,4 ]
Dahmani, Souhayl [1 ,2 ,3 ]
机构：
[1] Univ Paris, Paris, France
[2] Robert Debre Hosp, Dept Anesthesia & Intens Care, 48 Blvd Serurier, F-75019 Paris, France
[3] Robert Debre Hosp, DMU PROTECT, 48 Blvd Serurier, F-75019 Paris, France
[4] Robert Debre Hosp, Dept Orthoped Surg, 48 Blvd Serurier, F-75019 Paris, France
来源：
PAIN MANAGEMENT | 2021年 / 11卷 / 06期
关键词：
adolescent idiopathic scoliosis; fast track rehabilitation; opioid-free anesthesia; persistent neuropathic pain; posterior fusion; POSTOPERATIVE PAIN MANAGEMENT; DOSE INTRATHECAL MORPHINE; SPINAL-FUSION; NEUROPATHIC PAIN; DOUBLE-BLIND; METAANALYSIS; DEXAMETHASONE; ANALGESIA; KETAMINE; NAUSEA;
D O I：
10.2217/pmt-2020-0100
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Aims: Opioid-reduced anesthesia (ORA) was suggested to decrease morphine consumption after adolescent idiopathic scoliosis (AIS) surgery and incidence of chronic pain. Materials & methods: A prospective analysis using the ORA in AIS surgery was performed. Two cohorts were compared: a control group (opioid-based anesthesia) and the ORA group. The main outcome was morphine consumption at day 1. Results: 33 patients operated for AIS using ORA were compared with 36 with opioid-based anesthesia. Morphine consumption was decreased in the ORA group (1.1 mg.kg(-1) [0.2-2] vs 0.8 mg.kg(-1) [0.3-2]; p = 0.02) at day 1. Persistent neuropathic pain at 1 year was decreased in the ORA group (p = 0.02). Conclusion: The ORA protocol is efficient to reduce postoperative morphine consumption in AIS surgery and preventing neuropathic pain.
引用
收藏
页码：679 / 687
页数：9
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