Vascular factors in dementia: an overview

被引：66
作者：
DeCarli, C [1 ]
机构：
[1] Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2004年 / 226卷 / 1-2期
关键词：
dementia; Alzheimer disease; cerebrovascular disease;
D O I：
10.1016/j.jns.2004.09.005
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Alzheimer's disease and cerebrovascular disease are two illnesses common to the elderly. Conventional wisdom has sought to separately describe and treat these two diseases. Accumulating evidence, however, shows that cerebrovascular risk factors may cause asymptomatic brain injury, share genetic risk with Alzheimer's disease and possibly accelerate the Alzheimer's process. Such evidence suggests that these two diseases may act additively or synergistically to cause clinical dementia. This review focuses on evolving data that support this hypothesis. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：19 / 23
页数：5
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