Guidelines for optimization and scale-up in preparative chromatography

被引：0
|
作者：
Rathore, A
Velaydhan, A
机构：
[1] Pharmacia Corp, Chesterfield, MO 63017 USA
[2] Oregon State Univ, Dept Bioengn, Corvallis, OR 97331 USA
来源：
BIOPHARM INTERNATIONAL | 2003年 / 16卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Optimizing your purification and separation process when your complex biological feedstock is ready for scale-up can be daunting. Your design process can be streamlined, simplified, and made cost efficient if you supplement your empirical approach with the theoretical and experimental tools presented in this article.
引用
收藏
页码：34 / +
页数：8
相关论文
共 50 条
  • [1] Scale-up problems in preparative chromatography
    Piatkowski, W
    INZYNIERIA CHEMICZNA I PROCESOWA, 2005, 26 (03): : 605 - 630
  • [2] SCALE-UP FOR PREPARATIVE LIQUID-CHROMATOGRAPHY OF FINE CHEMICALS
    PIERI, G
    PICCARDI, P
    MURATORI, G
    CAVALLO, L
    CHIMICA & L INDUSTRIA, 1983, 65 (05): : 331 - 336
  • [3] OPTIMIZATION AND SCALE-UP OF AFFINITY-CHROMATOGRAPHY
    CHASE, HA
    BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 1987, 368 (07): : 738 - 738
  • [4] OPTIMIZATION AND SCALE-UP OF AFFINITY-CHROMATOGRAPHY
    CHASE, HA
    MAKROMOLEKULARE CHEMIE-MACROMOLECULAR SYMPOSIA, 1988, 17 : 467 - 482
  • [5] Evaluation of scale-up from analytical to preparative supercritical fluid chromatography
    Enmark, Martin
    Asberg, Dennis
    Leek, Hanna
    Ohlen, Kristina
    Klarqvist, Magnus
    Samuelsson, Jorgen
    Fornstedt, Torgny
    JOURNAL OF CHROMATOGRAPHY A, 2015, 1425 : 280 - 286
  • [6] SCALE-UP OF PREPARATIVE LIQUID-CHROMATOGRAPHY FOR PURIFICATION OF MACROLIDE ANTIBIOTICS
    KAWAI, T
    EGASHIRA, R
    ITSUKI, H
    KAWASAKI, J
    KAGAKU KOGAKU RONBUNSHU, 1993, 19 (04) : 680 - 683
  • [7] SCALE-UP AND OPTIMIZATION IN PRODUCTION LIQUID-CHROMATOGRAPHY
    WILHELM, AM
    RIBA, JP
    JOURNAL OF CHROMATOGRAPHY, 1989, 484 : 211 - 223
  • [8] Scale-up and productivity optimization for protein a chromatography.
    Shukla, AA
    Hinckley, P
    Hubbard, B
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U215 - U215
  • [9] Scale up in preparative chromatography
    Heuer, C
    Hugo, P
    Mann, G
    SeidelMorgenstern, A
    JOURNAL OF CHROMATOGRAPHY A, 1996, 752 (1-2) : 19 - 29
  • [10] PREPARATIVE ION-EXCHANGE CHROMATOGRAPHY - OPTIMIZATION AND SCALE UP
    BEADLING, LC
    SOFER, G
    MASON, C
    CHOJNACKI, R
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1986, 192 : 69 - MBTD
12345