MicroRNAs in Cardiovascular Biology and Heart Disease

被引：84
作者：
Catalucci, Daniele [1 ]
Gallo, Paolo [2 ,3 ]
Condorelli, Gianluigi [1 ,4 ]
机构：
[1] Ist Ricovero & Cura Carattere Sci Multimed, I-20138 Milan, Italy
[2] Campus BioMedico Univ, Dept Cardiovasc Med, Rome, Italy
[3] Campus BioMedico Univ, Fdn San Raffaele, Rome, Italy
[4] Univ Calif San Diego, Dept Med, Div Cardiol, La Jolla, CA 92093 USA
来源：
CIRCULATION-CARDIOVASCULAR GENETICS | 2009年 / 2卷 / 04期
关键词：
cardiovascular diseases; genes; myocardium; microRNA; heart failure; cardiac hypertrophy; antagomirs; MUSCLE-SPECIFIC MICRORNA; EMBRYONIC STEM-CELLS; CHANNEL GENES HCN2; CARDIAC-HYPERTROPHY; MESSENGER-RNA; VASCULAR INTEGRITY; TARGET RECOGNITION; IN-VIVO; EXPRESSION; DICER;
D O I：
10.1161/CIRCGENETICS.109.857425
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
MicroRNAs play important roles in many cellular and biological functions via the regulation of mRNA target translation. In the cardiovascular field, microRNAs are now acknowledged as fundamental in regulating the expression of genes that governs physiological and pathological myocardial adaptation to stress. Here, we review recent progress in the understanding of microRNA functions and their involvement in heart disease. (Circ Cardiovasc Genet. 2009; 2: 402-408.)
引用
收藏
页码：402 / 408
页数：7
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