Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli

被引:10
作者
Vandova, Gergana A. [1 ,2 ]
O'Brien, Robert V. [3 ]
Lowry, Brian [4 ]
Robbins, Thomas F. [3 ]
Fischer, Curt R. [1 ,5 ]
Davis, Ronald W. [1 ,2 ]
Khoslas, Chaitan [3 ,4 ,5 ]
Harvey, Colin J. B. [1 ]
Hillenmeyer, Maureen E. [1 ]
机构
[1] Stanford Univ, Stanford Genome Technol Ctr, Palo Alto, CA 94304 USA
[2] Stanford Univ, Dept Biochem, Palo Alto, CA 94304 USA
[3] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
[4] Stanford Univ, Dept Chem Engn, Stanford, CA 94305 USA
[5] Stanford Univ, Stanford ChEM H Inst, Stanford, CA 94305 USA
关键词
6-DEOXYERYTHRONOLIDE B; PROTEIN EXPRESSION; CRYSTAL-STRUCTURE; ACETYL-COA; BIOSYNTHESIS; ENZYME; COENZYME; SYNTHASE; GENES;
D O I
10.1038/ja.2017.38
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
[No abstract available]
引用
收藏
页码:859 / 863
页数:5
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