Erythropoietin-producing renal cell carcinoma in chronic hemodialysis patients: A report of two cases

被引:8
|
作者
Sakamoto, S [1 ]
Igarashi, T [1 ]
Osumi, N [1 ]
Imamoto, T [1 ]
Tobe, T [1 ]
Kamiya, M [1 ]
Ito, H [1 ]
机构
[1] Chiba Univ, Dept Urol, Grad Sch Med, Chuo Ku, Chiba 2608670, Japan
关键词
erythropoietin; hemodialysis; renal cell carcinoma;
D O I
10.1046/j.1442-2042.2003.00568.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Erythropoietin (EPO)-producing renal cell carcinomas in two hemodialysis patients are reported. Despite deteriorated kidney function, these patients did not manifest anemia at diagnosis and their elevated serum EPO levels rapidly returned to within the normal range after nephrectomy. Immunohistochemical staining of the resected specimens showed production of erythropoietin in the tumor cells in one case and in the lining cells of the cyst wall in the other case. Renal cell carcinoma could cause an increase of blood hematocrit level in dialysis patients.
引用
收藏
页码:49 / 51
页数:3
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